{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T08:11:29Z","timestamp":1781165489478,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>We report the prevalence, characteristics and clinical outcomes of women with sexually transmitted infections (STIs) in pregnancy in the Western Sydney Local Health District (WSLHD) serving a large culturally and socio\u2010economically diverse community in New South Wales (NSW), Australia, over the last 10\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study of all pregnant women booked for antenatal care at three hospitals in WSLHD between September 2012 and August 2022 inclusive. Characteristics and birth outcomes associated with STIs diagnosed in pregnancy (chlamydia, gonorrhea, and syphilis) are reported using multivariable logistic regression adjusting for relevant confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During 2012\u20132022, there were 102\u2009905 births and 451 women (0.44%) with an STI diagnosis during pregnancy. The number of women with a history of chlamydia prior to their current pregnancy has increased over the last 10\u2009years (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). STIs in pregnancy were more common in younger women aged &lt;20\u2009years (adjusted odds ratio [aOR] 7.30, 95% confidence interval [CI] 5.04\u201310.57), 20\u201324\u2009years (aOR 3.12, 95% CI 2.46\u20133.96), and &gt;40\u2009years (adj OR 1.67, 95% CI 1.07\u20132.59), in women with body mass index &gt;30 (aOR 1.73, 95%CI 1.37\u20132.19), and those who smoked (aOR 2.24, 95% CI 1.71\u20132.94) and consumed alcohol (aOR 3.14, 95% CI 1.88\u20135.23) and illicit drugs (aOR 2.10, 95% CI 1.31\u20133.36). STIs in pregnancy were borderline associated with stillbirth (aOR 2.19 95% CI 0.90\u20135.36) but did not have a significant impact on preterm birth (aOR 1.21, 95% CI 0.87\u20131.68), admission to neonatal intensive care unit (NICU) (aOR 1.02, 95% CI 0.77\u20131.34), or having a small\u2010for\u2010gestational\u2010age (SGA) baby (aOR 0.97, 95% CI 0.74\u20131.27).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Sociodemographic factors such as age, weight, smoking, and alcohol and drug use, were associated with the STI incidence in pregnancy. While the latter did not have an impact on preterm birth, NICU admission, and SGA in our cohort, there was a borderline association with stillbirth. Future research should identify barriers and facilitators to testing in a multicultural population and understanding the drivers of higher rates of STIs in certain population groups.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.15548","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T07:24:58Z","timestamp":1713943498000},"page":"107-114","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Sexually transmitted infections: Prevalence and clinical outcomes among pregnant women in Western Sydney"],"prefix":"10.1002","volume":"166","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5809-6883","authenticated-orcid":false,"given":"I.","family":"Ju","sequence":"first","affiliation":[{"name":"Reproduction and Perinatal Centre, Faculty of Medicine and Health University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Obstetrics and Gynaecology Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Elhindi","sequence":"additional","affiliation":[{"name":"Reproduction and Perinatal Centre, Faculty of Medicine and Health University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hook","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. J.","family":"Melov","sequence":"additional","affiliation":[{"name":"Reproduction and Perinatal Centre, Faculty of Medicine and Health University of Sydney  Sydney New South Wales Australia"},{"name":"Westmead Institute of Maternal Fetal Medicine Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Sawleshwarkar","sequence":"additional","affiliation":[{"name":"Western Sydney Sexual Health Centre  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. M.","family":"Yapa","sequence":"additional","affiliation":[{"name":"Sydney Infectious Diseases Institute, Faculty of Medicine &amp; Health University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Zablotska","sequence":"additional","affiliation":[{"name":"Western Sydney Sexual Health Centre  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Pasupathy","sequence":"additional","affiliation":[{"name":"Reproduction and Perinatal Centre, Faculty of Medicine and Health University of Sydney  Sydney New South Wales Australia"},{"name":"Westmead Institute of Maternal Fetal Medicine Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Health Organization.WHO sexually transmitted infections (STIs): [WHO website].2023. 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