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This case report presents an incidental finding of endometrial cancer with Lynch syndrome during investigation for primary infertility. A 34\u2010year\u2010old woman presented to the fertility clinic with unexplained primary infertility. Investigations showed possible endometrial polyp, 13\u2009\u00d7\u200911\u2009mm in size. Hysteroscopic polypectomy and endometrial biopsy revealed complex endometrial hyperplasia amounting to endometroid adenocarcinoma. The case was discussed at the West of Scotland Gynecology\u2010Oncology MDT meeting\u2014management options including fertility\u2010sparing treatment or radical surgery were presented to the patient and she opted for the latter. A total laparoscopic hysterectomy with bilateral salpingo\u2010oophorectomy was performed with pathology results consistent with well\u2010differentiated endometroid adenocarcinoma Stage 1A. Peritoneal washings showed no malignant cells. Genetic testing confirmed a diagnosis of Lynch syndrome. On further questioning, it was revealed that the patient had a strong family history of colon cancer but had not previously met the criteria for genetic testing. She was referred to colorectal surgeons and underwent colonoscopy. This showed no abnormality; she was therefore scheduled for 2\u2010yearly colonoscopic surveillance.<\/jats:p>","DOI":"10.1002\/ijgo.15578","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T04:25:34Z","timestamp":1714623934000},"page":"58-61","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Asymptomatic endometrial cancer with Lynch syndrome; in a woman with primary infertility\u2014A case report and literature review"],"prefix":"10.1002","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9998-3569","authenticated-orcid":false,"given":"Nancy","family":"Noah","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, University Hospital Wishaw NHS Lanarkshire  Wishaw UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7174-4080","authenticated-orcid":false,"given":"Misha","family":"Gilani","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, University Hospital Wishaw NHS Lanarkshire  Wishaw UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranitha","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, University Hospital Wishaw NHS Lanarkshire  Wishaw UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/tog.12706"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-309675"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2004\/305058"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-10-0345"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.743"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S283668"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.04.001"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.435"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(99)70510-X"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djh034"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2016.0108"},{"key":"e_1_2_8_13_1","unstructured":"National Institute for Health and Care Excellence.Testing strategies for Lynch syndrome in people with endometrial cancer. 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