{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:26:04Z","timestamp":1772990764453,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp;amp; Obste"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the incidence of uterovaginal anomalies and histologic findings in transgender and nonbinary (TGNB) patients seeking hysterectomies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All patients receiving gender\u2010affirming hysterectomies between 2013 and 2023 were retrospectively reviewed. Primary outcomes included uterovaginal anomalies and histological findings. Multivariable logistic regressions were performed to evaluate relationships between variables of interest and whether they predict findings of uterovaginal anomalies, inactive endometrium, adenomyosis, leiomyoma, endometriosis, and cervical atrophy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>278 patients received hysterectomies at an average age of 29.2\u2009\u00b1\u20098.3\u2009years. Seven patients (2.5%) were found to have a developmental anomaly, including two bicornuate uterus (0.7%), two unicornuate uterus (0.7%), one septate uterus (0.4%), and two vaginal septum (0.7%). 60 patients (21.6%) were found to have inactive endometrium and 26 patients (9.4%) had cervical atrophy. Although 262 patients (94.2%) were on testosterone therapy, hormone duration was not a significant predictor of any uterine findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study describes uterovaginal anomalies in a large cohort of patients receiving gender\u2010affirming hysterectomies. Although long\u2010term testosterone use is commonly believed to be associated with endometrial and cervical atrophy, this study shows no such association.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.15582","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T03:34:59Z","timestamp":1714966499000},"page":"230-236","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Developmental uterovaginal anomalies and histologic findings in transgender patients receiving gender\u2010affirming hysterectomies: A large case series"],"prefix":"10.1002","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2512-7269","authenticated-orcid":false,"given":"Nghiem H.","family":"Nguyen","sequence":"first","affiliation":[{"name":"Kaiser Permanente Bernard J. Tyson School of Medicine  Pasadena California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoejeong","family":"Kim","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Bernard J. Tyson School of Medicine  Pasadena California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Tran","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Bernard J. Tyson School of Medicine  Pasadena California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Sumida","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kaiser Permanente Southern California Medical Group  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Lansdowne","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Bernard J. Tyson School of Medicine  Pasadena California USA"},{"name":"Department of Obstetrics and Gynecology Kaiser Permanente Southern California Medical Group  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosanna","family":"Galzote\u2010Carino","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Bernard J. Tyson School of Medicine  Pasadena California USA"},{"name":"Department of Obstetrics and Gynecology Kaiser Permanente Southern California Medical Group  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2011.02348.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/lgbt.2019.0212"},{"key":"e_1_2_8_4_1","unstructured":"TangprichaV SaferJ SnyderP MatsumotoA MartinK.Transgender Men: Evaluation and Management. UpToDate. 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