{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:02:34Z","timestamp":1790730154009,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T00:00:00Z","timestamp":1720396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Congenital uterine anomalies include a wide diversity of uterine malformations that can compromise reproductive potential. Uterus transplantation (UTx) proposes an innovative treatment for absolute uterine factor infertility; however, there is a lack of standardized protocols to guide clinical management among this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe recipient and donor characteristics and obstetric outcomes in patients undergoing UTx.<\/jats:p><\/jats:sec><jats:sec><jats:title>Search Strategy<\/jats:title><jats:p>We performed a literature search using the PubMed database to retrieve available scientific articles. We analyzed the references of included articles to assess additional articles that could be eligible to be included in the review. Likewise, we identified further studies using other methods, including Google Scholar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Selection Criteria<\/jats:title><jats:p>Titles and abstracts were screened in duplicate to select original reports with information available for the outcomes of interest.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Collection and Analysis<\/jats:title><jats:p>This review assessed the advantages and disadvantages of the techniques used, patient characteristics, obstetric and non\u2010obstetric complications, functional duration of the organ, and neonatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Results<\/jats:title><jats:p>Among the 36 reports included in this review we found 55 pregnancies and 38 live births following UTx and a higher success rate for in\u00a0vivo uterine donations. The most common obstetric complications reported included miscarriage, pre\u2010eclampsia, and gestational hypertension. The most common non\u2010obstetric complications reported include episodes of rejection, acute kidney injury, anemia, and cholestasis. Living donors required a comprehensive preoperative workup, decreasing organ rejection, infection, and vascular complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>More studies are needed to standardize the UTx procedure and improve obstetric, fetal, and neonatal outcomes. Further understanding of which recipient and donor characteristics minimize complications will significantly decrease the risk of adverse outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.15752","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T05:37:43Z","timestamp":1720503463000},"page":"921-933","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Uterus transplantation: A scoping review focused on obstetric outcomes"],"prefix":"10.1002","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6833-1329","authenticated-orcid":false,"given":"Megan","family":"Barragan\u2010Wolff","sequence":"first","affiliation":[{"name":"Public Health and Epidemiology Division Universidad Panamericana School of Medicine  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6336-9423","authenticated-orcid":false,"given":"Martha S.","family":"Espinosa\u2010Cervantes","sequence":"additional","affiliation":[{"name":"Public Health and Epidemiology Division Universidad Panamericana School of Medicine  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8037-2036","authenticated-orcid":false,"given":"Sandra","family":"Acevedo\u2010Gallegos","sequence":"additional","affiliation":[{"name":"Maternal\u2010Fetal Medicine Division Instituto Nacional de Perinatologia  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J.","family":"Rodriguez\u2010Sibaja","sequence":"additional","affiliation":[{"name":"Maternal\u2010Fetal Medicine Division Instituto Nacional de Perinatologia  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5378-5724","authenticated-orcid":false,"given":"Mario I.","family":"Lumbreras\u2010Marquez","sequence":"additional","affiliation":[{"name":"Public Health and Epidemiology Division Universidad Panamericana School of Medicine  Mexico City Mexico"},{"name":"Maternal\u2010Fetal Medicine Division Instituto Nacional de Perinatologia  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J.","family":"Ito\u2010Esparza","sequence":"additional","affiliation":[{"name":"Public Health and Epidemiology Division Universidad Panamericana School of Medicine  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13050716"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cge.12883"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr028"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-020-01491-9"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0232323"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.02.024"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61728-1"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0000000000000936"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/M18-0850"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.04.001"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.5935\/1518-0557.20170028"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13853"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43043-020-00041-4"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14737"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.03.001"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004244"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2021.02.037"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12206463"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)31766-5"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.13992"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003346"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2020.03.006"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9082485"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2020.06.007"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005346"},{"key":"e_1_2_9_27_1","first-page":"339","volume-title":"Live birth from the World's first\u2010ever successful uterus transplant and the following second case from Turkey: technical aspects, surgical and obstetric outcomes","author":"\u00d6zkan O","year":"2023"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12082812"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004199"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2022.2612"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2020.12.015"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10040586"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000004437"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0000000000000678"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003633"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-021-02245-7"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.15863"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2022.05.017"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16685"},{"key":"e_1_2_9_40_1","volume-title":"Antenatal Corticosteroid Therapy for Fetal Maturation","author":"El\u2010Sayed Y","year":"2017"},{"issue":"1","key":"e_1_2_9_41_1","first-page":"42","article-title":"Neonatal outcomes after uterus transplantation: Dallas uterus transplant study","volume":"40","author":"York JR","year":"2021","journal-title":"Am J Perinatol"},{"issue":"10","key":"e_1_2_9_42_1","first-page":"905","article-title":"Safety of tacrolimus in pregnancy","volume":"60","author":"Nevers W","year":"2014","journal-title":"Can Fam Physician"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13757"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S75635"},{"issue":"8","key":"e_1_2_9_45_1","article-title":"Navigating through the complications of chronic immunosuppression in transplant patients","volume":"1","author":"Amaeshi LC","year":"2022","journal-title":"Annal Intern Med"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-016-0215-7"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.15752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T05:34:07Z","timestamp":1731735247000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.15752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,8]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/ijgo.15752"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.15752","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,8]]},"assertion":[{"value":"2024-03-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}