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The World Health Organization acknowledges its severe impact on quality of life due to pain, fatigue, depression, and infertility. There is limited literature on the prevalence of endometriosis, knowledge of which is essential for effective prevention, treatment strategies, and funding. We aim to structure and present the published data on endometriosis prevalence, synthesizing the discrepancy between health insurance and clinical data. PubMed, Cochrane CENTRAL, and LIVIVO were researched for peer\u2010reviewed articles published between January 2000 and July 2023 on women of reproductive age. Health insurance companies argue that few women (~1%) are affected by endometriosis. Interestingly, the prevalence of clinical data studies (6.8%), population\u2010based surveys\/self\u2010reported studies (6.6%), and symptomatic patient data (21%) revealed a different picture. Based on the data gathered, a multi\u2010layered prevalence model has been proposed to illustrate the large discrepancy in the prevalence numbers, leading to the disease being underestimated and underfunded.\u2009This variability may be influenced by the heterogeneity in designs and the analyzed data, and\u2009clinical complexity. In summary, this narrative review reveals that the prevalence of endometriosis is higher than health insurance and other stakeholders might have previously assumed.<\/jats:p>","DOI":"10.1002\/ijgo.15756","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T06:10:12Z","timestamp":1721369412000},"page":"883-900","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Assessing the true prevalence of endometriosis: A narrative review of literature data"],"prefix":"10.1002","volume":"167","author":[{"given":"Carolin","family":"Harder","sequence":"first","affiliation":[{"name":"Department of Gynecology Charit\u00e9 with Center of Oncological Surgery, Endometriosis Research Center Charit\u00e9  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0788-1640","authenticated-orcid":false,"given":"Renata 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