{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T13:14:18Z","timestamp":1788095658420,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:00:00Z","timestamp":1721001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mental health disorders in pregnant women have been related to unfavorable obstetric and neonatal outcomes. Obsessive\u2010compulsive disorder (OCD) significantly distresses mothers and affects the maternal\u2013infant bond.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The present meta\u2010analysis and systematic review aimed to assess the association of maternal OCD with adverse feto\u2010maternal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Search Strategy<\/jats:title><jats:p>A systematic search was undertaken in the five databases\u2014Cochrane, Embase, ProQuest, Web of Science, and PubMed\u2014on September 5, 2023.<\/jats:p><\/jats:sec><jats:sec><jats:title>Selection Criteria<\/jats:title><jats:p>Studies that included pregnant women with OCD in whom the feto\u2010maternal outcomes were reported were included in the systematic review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Collection and Analysis<\/jats:title><jats:p>Two pass screening (\u201ctitle\u2010abstract screening\u201d followed by \u201cfull\u2010text review\u201d), and data extraction by two authors independently using the Nested\u2010Knowledge Auto living semi\u2010automated systematic review platform was carried out. The decision for selected studies was reviewed by a third author. Of the 360 studies identified, eight were included for the meta\u2010analysis. Meta\u2010analysis was conducted using R software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Results<\/jats:title><jats:p>Of the 24 maternal and neonatal adverse outcomes assessed, 11 were found to be associated with maternal OCD, notably pre\u2010eclampsia (odds ratio [OR] 1.37, 95% confidence interval [CI] 1.19\u20131.57), antepartum hemorrhage or placental abruption (OR 1.32, 95% CI 1.13\u20131.54), postpartum hemporrhage (OR 1.19, 95% CI 1.08\u20131.31), cesarean section delivery (OR 1.32, 95% CI 1.23\u20131.41), emergency cesarean section (OR 1.22, 95% CI 1.15\u20131.30), preterm birth (OR 1.41, 95% CI 1.21\u20131.64), low birth weight (OR 1.41, 95% CI 1.28\u20131.54), low Apgar score at 5\u2009min (OR 2.37, 95% CI 1.32\u20134.27), neonatal hypoglycemia (OR 1.37, 95% CI 1.23\u20131.53), neonatal respiratory distress (OR 1.77, 95% CI 1.44\u20132.16), and major congenital malformations (OR 1.37, 95% CI 1.08\u20131.74).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>OCD in pregnant women might be associated with multiple adverse feto\u2010maternal outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.15792","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T11:24:09Z","timestamp":1721042649000},"page":"949-956","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effect of maternal obsessive\u2010compulsive disorder (<scp>OCD<\/scp>) on feto\u2010maternal outcomes: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"167","author":[{"given":"Savvy","family":"Aujla","sequence":"first","affiliation":[{"name":"Government Medical College  Amritsar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mokanpally","family":"Sandeep","sequence":"additional","affiliation":[{"name":"School of Medical Sciences University of 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