{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:45:42Z","timestamp":1786977942493,"version":"build-2736575974"},"reference-count":51,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T00:00:00Z","timestamp":1727308800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T00:00:00Z","timestamp":1727308800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Literature is lacking strong evidence about comparisons of efficacy and quality of life\u2010related outcomes between laparoscopic total and\/or supracervical hysterectomy (LTH\/LSCH) with laparoscopic sacrocolpopexy (LSC) and minimally invasive sacrohysteropexy (LSH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To summarize and compare available data on this topic providing a useful clinical tool in the treatment decision process.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Search Strategy<\/jats:title>\n                    <jats:p>We performed a systematic research of PubMed (MEDLINE), Web of Science, and Gooogle Scholar.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Selection Criteria<\/jats:title>\n                    <jats:p>We included studies that compared at least one efficacy outcome (objective or subjective outcome) between LTH\/LSCH with LSC and LSH. Data on surgery\u2010related morbidities were also extracted where available.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Collection and Analysis<\/jats:title>\n                    <jats:p>A random\u2010effect meta\u2010analysis was conducted reporting pooled mean differences and odds ratios (OR) between groups using Review Manager V.7.9.0.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Results<\/jats:title>\n                    <jats:p>\n                      We included a total of nine observational studies. LTH\/LSCH with LSH was associated with a significantly higher objective success (apical compartment OR 7.95; 95% confidence interval [CI] 2.23\u201328.33;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001; anterior compartment OR 2.23; 95% CI 1.26\u20134.30;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200912%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.007) and subjective success (OR 3.19; 95% CI 1.42\u20137.17;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200939%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.005). No differences were found regarding intraoperative and postoperative complications, sexual dysfunction, and stress urinary incontinence rate after surgery. Hysteropexy showed shorter operative time and shorter hospital length with a pool mean difference of 27.37\u2009min (95% CI 18.04\u201332.71;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) and 0.7\u2009days (95% CI 0.24\u20131.17;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200975%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.003), respectively. Concurrent hysterectomy was not associated with a higher rate of mesh\u2010related complications (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.53). No major differences were found regarding recurrence and reoperation rate (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.10 and\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.93, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>LTH\/LSCH with LSC has better objective and subjective outcomes in pelvic organ prolapse surgery than LSH alone, especially for apical and anterior compartments, and is not associated with higher postoperative sexual dysfunction and mesh\u2010related complications. Adequate preoperative counseling is highly recommended in patients who desire uterine preservation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>\n                      <jats:styled-content style=\"fixed-case\">PROSPERO<\/jats:styled-content>\n                      Registration Number\n                    <\/jats:title>\n                    <jats:p>CRD42024537270.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.15891","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T06:43:16Z","timestamp":1727332996000},"page":"456-471","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Laparoscopic sacrocolpopexy with concurrent hysterectomy or uterine preservation: A metanalysis and systematic review"],"prefix":"10.1002","volume":"168","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-6178-2233","authenticated-orcid":false,"given":"Veronica","family":"Tius","sequence":"first","affiliation":[{"name":"Medical Area Department (DAME), in Department of Medicine (DMED) University of Udine  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8257-0618","authenticated-orcid":false,"given":"Martina","family":"Arcieri","sequence":"additional","affiliation":[{"name":"Clinic of Obstetrics and Gynecology \u201cS. Maria della Misericordia\u201d University Hospital, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC)  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Taliento","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences Institute of Obstetrics and Gynecology, University of Ferrara  Ferrara Italy"},{"name":"Department of Development and Regeneration\u2014Woman and Child KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0644-0301","authenticated-orcid":false,"given":"Giulia","family":"Pellecchia","sequence":"additional","affiliation":[{"name":"Medical Area Department (DAME), in Department of Medicine (DMED) University of Udine  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampiero","family":"Capobianco","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Gynecologic and Obstetric Clinic University of Sassari  Sassari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Simoncini","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Panico","sequence":"additional","affiliation":[{"name":"Department of Woman and Child's Health and Public Health, Division of Urogynecology and Reconstructive Surgery of Pelvic Floor Fondazione Policlinico Universitario Agostino Gemelli IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Caramazza","sequence":"additional","affiliation":[{"name":"Precision Gynecological Surgery Unit, Dipartimento Centro di Eccellenza Donna e Bambino Nascente Fatebenefratelli Gemelli Isola Tiberina  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Campagna","sequence":"additional","affiliation":[{"name":"Precision Gynecological Surgery Unit, Dipartimento Centro di Eccellenza Donna e Bambino Nascente Fatebenefratelli Gemelli Isola Tiberina  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenza","family":"Driul","sequence":"additional","affiliation":[{"name":"Medical Area Department (DAME), in Department of Medicine (DMED) University of Udine  Udine Italy"},{"name":"Clinic of Obstetrics and Gynecology \u201cS. Maria della Misericordia\u201d University Hospital, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC)  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Scambia","sequence":"additional","affiliation":[{"name":"Department of Woman and Child's Health and Public Health Fondazione Policlinico Universitario Agostino Gemelli IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Ercoli","sequence":"additional","affiliation":[{"name":"Department of Human Pathology in Adult and Childhood \u201cG. Barresi\u201d, Unit of Gynecology and Obstetrics University of Messina  Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7848-0329","authenticated-orcid":false,"given":"Stefano","family":"Restaino","sequence":"additional","affiliation":[{"name":"Clinic of Obstetrics and Gynecology \u201cS. 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