{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T01:18:36Z","timestamp":1773451116128,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,9,22]],"date-time":"2024-09-22T00:00:00Z","timestamp":1726963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,9,22]],"date-time":"2024-09-22T00:00:00Z","timestamp":1726963200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100009131","name":"Direktion f\u00fcr Entwicklung und Zusammenarbeit","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009131","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Lack of accessibility to oral glucose tolerance tests (OGTTs) in South Africa means many pregnant women go without testing for gestational diabetes mellitus (GDM). This study evaluated point\u2010of\u2010care (POC) glucometers against the laboratory\u2010based glucose method in pregnant women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a cross\u2010sectional study on pregnant women attending the prenatal clinic in Johannesburg who were recommended for the OGTT. OGTTs were conducted as per International Association of Diabetes and Pregnancy Study Groups (IADPSG) guidelines. Women who consented to the study donated both venous and capillary blood for laboratory\u2010based and POC glucose measurements using seven POC glucometers: I\u2010STAT, Xpress, LDX, VivaChek\u2010Ino, Accu\u2010Chek Active, StatStrip, and Codefree. By assessing sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) and comparing Bland\u2013Altman plots, the diagnostic accuracy of each glucose meter was compared with the reference method, the laboratory\u2010based glucose method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Data were analyzed for 1076 pregnant women. Based on OGTT testing, 83 women had GDM (7.7%). Overall, the POC glucometers performed poorly, with sensitivity ranging from 17.6% to 87.18% and specificity ranging between 62.7% and 99.8%. The AUC ranged from 0.59 to 0.79. All POC glucometers showed moderate to poor reliability. Laboratory\u2010based fasting plasma glucose (FPG) surpassed the POC glucometers in sensitivity, specificity, and AUC, with values of 94.0%, 100%, and 0.98, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We demonstrated that laboratory\u2010based FPG has the potential to be used as a diagnostic test for GDM and that the POC glucometers cannot replace OGTT laboratory\u2010based measurements.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.15914","type":"journal-article","created":{"date-parts":[[2024,9,22]],"date-time":"2024-09-22T08:14:17Z","timestamp":1726992857000},"page":"812-821","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Performance of point\u2010of\u2010care glucose testing for the diagnosis of gestational diabetes in South Africa"],"prefix":"10.1002","volume":"168","author":[{"given":"L.","family":"Khambule","sequence":"first","affiliation":[{"name":"Department of Chemical Pathology University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Chikomba","sequence":"additional","affiliation":[{"name":"Department of Chemical Pathology University of the Witwatersrand  Johannesburg South Africa"},{"name":"Department of Chemical Pathology National Health Laboratory Service  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Adam","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Chris Hani Baragwanath Academic Hospital University of the Witwatersrand  Johannesburg South\u00a0Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Chemical Pathology University of the Witwatersrand  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Haldane","sequence":"additional","affiliation":[{"name":"FIND  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Vetter","sequence":"additional","affiliation":[{"name":"FIND  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"George","sequence":"additional","affiliation":[{"name":"Wits Diagnostic and Innovation Hub, National Health Laboratory Service  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2021.109050"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2017.03.024"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707943"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/3076463"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19113342"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(15)30033-3"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/inthealth\/ihab054"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2018.03.012"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.7196\/SAMJ.2019.v110i1.14089"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14255"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296818790228"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc23-1663"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcte.2018.12.003"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13178"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2016\/18129.8744"},{"issue":"1","key":"e_1_2_11_17_1","first-page":"S103","article-title":"The 2017 SEMDSA Guidelines for the Management of Type 2 Diabetes","volume":"22","author":"Veronique N","year":"2017","journal-title":"Journal of Endocrinology, Metabolism and Diabetes of South Africa"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-1848"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aew320"},{"key":"e_1_2_11_20_1","unstructured":"EFLM.Biological variation. 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