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A retrospective cohort study was conducted, analyzing data from pregnant patients diagnosed with PE between January 2015 and December 2019 at a tertiary care center in Brazil. Ethical approval was obtained, and the patient records were reviewed to assess maternal and perinatal outcomes based on the revised diagnostic criteria by the College of Obstetricians and Gynecologists, focusing on the presence or absence of proteinuria. The study included 816 pregnant patients with PE, of whom 685 (83.9%) were diagnosed based on proteinuria. The revised criteria, which include indicators of organ damage, identified an additional 131 cases (16.4%). Analysis showed no significant differences in maternal outcomes between proteinuria and non\u2010proteinuria groups, including intensive care unit (ICU) admission, acute pulmonary edema (APE), HELLP syndrome, eclampsia, or C\u2010section rates. However, babies born to mothers with proteinuria PE experienced worse outcomes, including fetal growth restriction, low birth weight, ICU admission, and higher rates of preterm birth. Relative risk analysis demonstrated a high risk of babies being born with low birth weight, ICU admission, and being born preterm and very preterm in cases where proteinuria was present in mothers with PE. The presence of proteinuria is associated with significantly worse outcomes in babies born to mothers with preeclampsia, while no significant differences were observed in maternal outcomes.<\/jats:p>","DOI":"10.1002\/ijgo.16007","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T14:39:33Z","timestamp":1730731173000},"page":"285-291","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Proteinuria is associated with worse outcomes in babies born to mothers with preeclampsia: A retrospective cohort study at a tertiary referral hospital in Brazil"],"prefix":"10.1002","volume":"169","author":[{"given":"Ana Clara","family":"Alves Ferreira","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo (USP)  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samara Mirelly","family":"dos Santos Guedes","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo (USP)  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara Cristina Gomes Ferraz","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo (USP)  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5270-6345","authenticated-orcid":false,"given":"Priscila Oliveira","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo (USP)  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5010-4914","authenticated-orcid":false,"given":"Ricardo de Carvalho","family":"Cavalli","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo (USP)  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2011.01.006"},{"key":"e_1_2_11_3_1","unstructured":"MageeLA vonDadelszenP StonesW MatthewsM.The FIGO Textbook of Pregnancy Hypertension: an Evidence\u2010Based Guide to Monitoring Prevention and Management. 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