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Based on gestational age, participants were categorized into three groups: very early preterm birth (&lt;28\u2009weeks), early preterm birth (\u226528 to &lt;34\u2009weeks), and ongoing pregnancy (\u226534\u2009weeks). Univariate analysis was conducted to assess general conditions, among the three groups. Multiple logistic regression analysis was performed to identify independent risk factors for very early and early spontaneous preterm birth in twin pregnancies. A total of 2042 twin pregnancies were included in the study, with birth rates of 4.36% (89 of 2042) &lt;28\u2009weeks, 12.14% (248 of 2042) \u226528 to &lt;34\u2009weeks, and 83.50% (1705 of 2042) \u226534\u2009weeks. The primary cause of provider\u2010initiated preterm birth &lt;28\u2009weeks was placental factors, while hypertensive disorders of pregnancy (31.11%) were the predominant cause for preterm births \u226528 to &lt;34\u2009weeks. Multiple logistic regression analysis identified the independent risk factors for births &lt;28\u2009weeks (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) as cervical cerclage, history of late miscarriage or premature birth, uterine adhesions, primary infertility of polycystic ovary syndrome (PCOS), monochorionic pregnancies, history of cervical surgery, uterine malformations, body mass index \u226525\u2009kg\/m<jats:sup>2<\/jats:sup>, and uterine longitudinal axis lengths &lt;3.6\u2009cm. Cervical cerclage, main factors of infertility (PCOS), adenomyosis, and uterine longitudinal axis lengths &lt;3.6\u2009cm were identified as independent risk factors for \u226528 to 34\u2009weeks (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). It is crucial to consider risk factors during IVF\/ICSI treatment because of the high incidence of very early and early preterm twin pregnancies, which can be identified early and properly managed.<\/jats:p>","DOI":"10.1002\/ijgo.16022","type":"journal-article","created":{"date-parts":[[2024,11,23]],"date-time":"2024-11-23T09:58:28Z","timestamp":1732355908000},"page":"372-382","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of risk factors for very early preterm and early preterm birth in twins following in\u00a0vitro fertilization and intracytoplasmic sperm injection\u2013assisted pregnancy: A\u00a0retrospective study"],"prefix":"10.1002","volume":"169","author":[{"given":"Huaying","family":"Yu","sequence":"first","affiliation":[{"name":"Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine Zhejiang University  Hangzhou China"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology  Hangzhou China"},{"name":"Zhejiang Key Laboratory of Precise Protection and Promotion of Fertility  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine Zhejiang University  Hangzhou China"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology  Hangzhou China"},{"name":"Zhejiang Key Laboratory of Precise Protection and Promotion of Fertility  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Chen","sequence":"additional","affiliation":[{"name":"Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine Zhejiang University  Hangzhou China"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology  Hangzhou China"},{"name":"Zhejiang Key Laboratory of Precise Protection and Promotion of Fertility  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minling","family":"Wei","sequence":"additional","affiliation":[{"name":"Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine Zhejiang University  Hangzhou China"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology  Hangzhou China"},{"name":"Zhejiang Key Laboratory of Precise Protection and Promotion of Fertility  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aike","family":"Xu","sequence":"additional","affiliation":[{"name":"Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine Zhejiang University  Hangzhou China"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, School of Medicine Zhejiang University  Hangzhou China"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology  Hangzhou China"},{"name":"Zhejiang Key Laboratory of Precise Protection and Promotion of Fertility  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,23]]},"reference":[{"issue":"13","key":"e_1_2_11_2_1","first-page":"1","article-title":"Births: final data for 2018","volume":"68","author":"Martin JA","year":"2019","journal-title":"National Vital Stat 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