{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T03:35:33Z","timestamp":1782272133218,"version":"3.54.5"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,22]],"date-time":"2024-12-22T00:00:00Z","timestamp":1734825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the proportion of small\u2010for\u2010gestational age (SGA) infants detected by routine care versus a growth assessment protocol using customized fundal\u2010height charts in low\u2010risk pregnancies of a developing country.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An open label randomized controlled trial was conducted at the Fatima Memorial Hospital (NUR International University, Pakistan). Low\u2010risk pregnant women were randomly allocated to routine care (Mcdonald's rule for fundal height measurements followed by referral for scan with discrepancy of 3\u2009cm from gestational age and a contingency third trimester scan) or the growth assessment protocol (GAP) developed by the Perinatal Institute (UK), which consists of the use of gestation\u2010related optimal weight (GROW) customized charts, alongside management protocols for suspected SGA fetuses, audit tools and training. The primary prespecified outcome was the detection of SGA (defined as a birthweight &lt;10th centile).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 2535 eligible women, 1884 (74%) were randomized (942 to standard care and 942 to GAP). After loss\u2010to\u2010follow\u2010up, 1755 women were analyzed (874 in the standard measurement group and 881 in the GAP group). The detection rate of SGA infants was higher in the GAP group (83.2% [95% CI: 74.4%\u201389.9%] vs. 29% [95% CI: 20.4%\u201338.9%], <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), at the cost of an increased false positive rate (10.4% [95% CI: 8.3%\u201312.7%] vs. 1.4% [95% CI: 0.7%\u20132.5%], <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The diagnostic odds ratio (positive likelihood ratio\/negative likelihood ratio) was 42.6 (95% CI: 24.1\u201375.4) in the GAP group and 28.3 (95% CI:13.6\u201359.1) in the standard care group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In low\u2010risk pregnant women of a developing country, a growth assessment protocol based on customized fundal\u2010height charts is superior to standard measurements for the antenatal detection of SGA in newborns.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.16107","type":"journal-article","created":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T07:43:30Z","timestamp":1734939810000},"page":"679-688","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["<scp>CustOmized<\/scp> versus standard fundal\u2010height <scp>measuREments<\/scp> for the detection of small\u2010for\u2010gestational age fetuses in low\u2010risk women (<scp>CORE<\/scp> study): A randomized controlled trial"],"prefix":"10.1002","volume":"169","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6074-8692","authenticated-orcid":false,"given":"Farhat ul Ain","family":"Ahmed","sequence":"first","affiliation":[{"name":"Fatima Memorial Hospital, NUR International University  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharoon","family":"Hanook","sequence":"additional","affiliation":[{"name":"Forman Christian College (A Chartered University)  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima","family":"Ismail","sequence":"additional","affiliation":[{"name":"Fatima Memorial Hospital, NUR International University  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima","family":"Shah","sequence":"additional","affiliation":[{"name":"Fatima Memorial Hospital, NUR International University  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maaz","family":"Arsalan","sequence":"additional","affiliation":[{"name":"Fatima Memorial Hospital, NUR International University  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria F.","family":"Lopez Garcia\u2010Tinajero","sequence":"additional","affiliation":[{"name":"BCNatal (Hospital Clinic and Hospital Sant Joan de Deu) Universitat de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judit","family":"Martinez\u2010Egea","sequence":"additional","affiliation":[{"name":"BCNatal (Hospital Clinic and Hospital Sant Joan de Deu) Universitat de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesc","family":"Figueras","sequence":"additional","affiliation":[{"name":"BCNatal (Hospital Clinic and Hospital Sant Joan de Deu) Universitat de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,22]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Every Newborn: An Action Plan to End Preventable Deaths","author":"World Health Organization","year":"2014"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(15)00275-2"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.12.004"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20282"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f108"},{"key":"e_1_2_11_7_1","unstructured":"Royal College of Obstetricians and Gynaecologists.The investigation and management of the small\u2010for\u2010gestational\u2010age fetus. 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