{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:07:26Z","timestamp":1787746046921,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T00:00:00Z","timestamp":1737158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100020010","name":"Centre for Intervention Science in Maternal and Child Health, University of Bergen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020010","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Negative pressure wound therapy (NPWT) is a very effective method in the treatment of dehiscent, infected, and non\u2010healing wounds. Difficult wound healing occurs especially in late pregnancy due to the rapid enlargement of the uterus and the constantly increasing tension of the entire abdominal wall. In cases of dehiscence of the surgical wound during pregnancy, proper subsequent treatment is needed, where it is necessary to consider the safety of the mother as well as the fetus. We report the case of a 30\u2010week pregnant patient who was surgically treated for acute appendicitis in pregnancy with an open appendectomy approach. Postoperative complications resulted in wound dehiscence with complete defect in fascia, which was treated with negative V.A.C. ATS\u00ae Therapy System. The therapy was started in the 30th week of pregnancy and continued until delivery with regular check\u2010ups and regular redressing of the vacuum\u2010assisted closure (VAC) system. At 38\u2009weeks of pregnancy, the patient delivered vaginally with continued VAC therapy in\u00a0situ. The final suture took place 3\u2009days after vaginal delivery. Non\u2010healing wounds with abdominal wall defects should be treated using a multidisciplinary approach, and NPWT can be used. This therapy can also be used during pregnancy. Vaginal delivery is preferred because it reduces the risk of further formation or deepening of the abdominal wall defect after a sufficient time interval from the start of the treatment. This complex case with a literature review of surgical complications in pregnancy treated with NPWT therapy highlights the advantage of a multidisciplinary approach.<\/jats:p>","DOI":"10.1002\/ijgo.16155","type":"journal-article","created":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T09:30:03Z","timestamp":1737192603000},"page":"150-156","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Abdominal wound dehiscence after appendectomy during pregnancy treated by negative pressure wound therapy with subsequent vaginal delivery: A case report and literature review"],"prefix":"10.1002","volume":"170","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2705-2970","authenticated-orcid":false,"given":"Jan","family":"Zapletal","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Third Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady  Prague 10 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2622-2181","authenticated-orcid":false,"given":"Borek","family":"Sehnal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Third Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady  Prague 10 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8493-2066","authenticated-orcid":false,"given":"Radim","family":"Dvorak","sequence":"additional","affiliation":[{"name":"Department of Surgery, Third Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady  Prague 10 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Drienko","sequence":"additional","affiliation":[{"name":"Department of Surgery, Third Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady  Prague 10 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radovan","family":"Vlk","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Third Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady  Prague 10 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3391-1412","authenticated-orcid":false,"given":"Michael J.","family":"Halaska","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Third Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady  Prague 10 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3770-651X","authenticated-orcid":false,"given":"Lukas","family":"Rob","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Third Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady  Prague 10 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12093277"},{"key":"e_1_2_9_3_1","unstructured":"Acute appendicitis in pregnancy \u2013 UpToDaten.d.https:\/\/www.uptodate.com\/contents\/acute\u2010appendicitis\u2010in\u2010pregnancy?search=appendicitis%20in%20pregnancy&source=search_result&selectedTitle=1%7E150&usage_type=default&display_rank=1. 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