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Stimulated patients should be monitored with ultrasound and estradiol levels as per normal clinic practice. For women with a diagnosis of breast cancer, and with the agreement of the treating oncologist, the stimulation protocol should include an aromatase inhibitor such as letrozole to reduce the circulating estradiol levels. All patients should have a gonadotropin\u2010releasing hormone trigger to eliminate the risk of ovarian hyperstimulation syndrome and facilitate timely return for cancer therapy.<\/jats:p>","DOI":"10.1002\/ijgo.16170","type":"journal-article","created":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T23:14:51Z","timestamp":1740870891000},"page":"876-878","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Fertility stimulation protocols in women with cancer"],"prefix":"10.1002","volume":"169","author":[{"given":"Nikhil C.","family":"Purandare","sequence":"first","affiliation":[{"name":"University Hospital Galway University of Galway  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian A.","family":"Ryan","sequence":"additional","affiliation":[{"name":"University Hospital Galway University of Galway  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"El Helali","sequence":"additional","affiliation":[{"name":"Centre of Cancer Medicine, Li Ka Shing Faculty of Medicine University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Crosby","sequence":"additional","affiliation":[{"name":"National Maternity Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.07.1333"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1546424"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.03.027"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/14647273.2017.1287433"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02744936"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-016-1526-3"},{"issue":"5","key":"e_1_2_9_8_1","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.1016\/j.fertnstert.2008.08.031","article-title":"Gonadotropin preparations: past, present and future perspectives","volume":"90","author":"Practice Committee of American Society for reproductive medicine, Birmingham, Alabama","year":"2008","journal-title":"Fertil Steril"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.29252\/ijrm.14.9.557"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)54474-4"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-014-0248-6"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0000000000000180"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dew051"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.04.041"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v8.i3.241"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2018.00317"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.8700"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.16170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T12:02:44Z","timestamp":1747828964000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.16170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,26]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1002\/ijgo.16170"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.16170","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,26]]},"assertion":[{"value":"2024-08-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}