{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:59:55Z","timestamp":1781744395208,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T00:00:00Z","timestamp":1738281600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare differences in maternal hemodynamics, measured non\u2010invasively by impedance cardiography and mean arterial blood pressure (MAP)\u2014at rest and with high\u2010intensity exercise\u2014between pregnant women with corrected congenital heart disease (CHD) and low\u2010risk (LR) pregnant controls, and to correlate these findings with umbilical artery Doppler in the third trimester, estimated fetal weight (EFW) and birth weight (BW).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective longitudinal study with hemodynamic exercise studies and fetal ultrasound between 30 and 34\u2009weeks' gestation. Approval was obtained from London South East Research Ethics Committee.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no differences in heart rate (HR), stroke volume (SV), or cardiac output (CO) at rest between the two groups. HR at peak exercise was significantly lower in the CHD group, and MAP was significantly higher at rest and immediately after exercise. In the CHD group there was a significant association between CO at peak exercise and BW. In the LR group there was a significant association between peak CO with exercise and the abdominal circumference\/EFW ratio and between HR at rest and BW. There were no differences in the Doppler indices between groups. There was a statistically significant association between uterine artery Doppler pulsatility index and BW in the LR group, but not in the CHD group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was no difference between Doppler indices in the third trimester between a LR population and a population with corrected CHD with no or minimal functional impairment. This suggests that factors other than defective placentation may be causing the lower BW in the CHD population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.16190","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T11:29:26Z","timestamp":1738322966000},"page":"361-369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Relationships of maternal hemodynamics in the third trimester with fetal umbilical artery doppler indices, estimated fetal weight and birth weight in women with and without congenital heart disease"],"prefix":"10.1002","volume":"170","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9301-8397","authenticated-orcid":false,"given":"Francois Dos","family":"Santos","sequence":"first","affiliation":[{"name":"Imperial College London, Chelsea And Westminster Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6099-2037","authenticated-orcid":false,"given":"Ellen","family":"Barr","sequence":"additional","affiliation":[{"name":"O&amp;G Department Fiona Stanley Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J.","family":"Steer","sequence":"additional","affiliation":[{"name":"Imperial College London, Chelsea And Westminster Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Imperial College London, Chelsea And Westminster Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2015-308946"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.01.069"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz136"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2018-313551"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.10.005"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5311"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20125"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.10.024"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20272"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12371"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBP.0b013e32831e305d"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2012.04.001"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1095"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2006.00945.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.12.007"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31820cab69"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.953380"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2007.07.007"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004210000226"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004210100458"},{"key":"e_1_2_9_22_1","volume-title":"Does Advanced Cardiac Impedance Technology Accurately Measure Cardiac Output during Submaximal Steady State Exercise? (Scientific Abstract)","author":"Broeder C","year":"2009"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002996"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3901"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.002810"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2015.1085012"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15938"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14697"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.16190","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T05:38:22Z","timestamp":1750311502000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.16190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,31]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/ijgo.16190"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.16190","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,31]]},"assertion":[{"value":"2024-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}