{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T20:03:01Z","timestamp":1783368181346,"version":"3.54.6"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp;amp; Obste"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate population characteristics and pregnancy, delivery, and neonatal complications in women with myomectomy prior to pregnancy versus intramural fibroids in\u00a0situ.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective cohort study using hospital discharge data from the Healthcare Cost and Utilization Project Nationwide Inpatient Sample from 2004 to 2014 included. A population of 14\u2009206 pregnancies post\u2010myomectomy and 81\u2009517 with fibroids in\u00a0situ were analyzed, performing multivariate logistic regression with adjustment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Post\u2010myomectomy patients were younger, with lower body mass index, higher in\u00a0vitro fertilization use, more commonly Caucasians or Hispanics, and had higher rates of pregestational diabetes, smoking, illicit drug use, previous cesarean delivery, and multiple gestations, compared with the in\u2010situ fibroid (ISF) group. Post\u2010myomectomy patients had decreased rates of gestational hypertension (adjusted odds ratio [aOR] 0.87, 95% confidence interval [CI] 0.77\u20130.97), eclampsia (aOR 0.76, 95% CI 0.32\u20130.81), gestational diabetes (aOR 0.83, 95% CI 0.77\u20130.90), spontaneous vaginal deliveries (aOR 0.09, 95% CI 0.08\u20130.11), postpartum hemorrhage (aOR 0.77, 95% CI 0.68\u20130.88), and intrauterine fetal death (aOR 0.64, 95% CI 0.43\u20130.97). Conversely, they had increased risks of placenta previa (aOR 1.40, 95% CI 1.20\u20131.64), preterm delivery (aOR 1.16, 95% CI 1.07\u20131.24), cesarean section (aOR 8.64, 95% CI 7.71\u20139.69), uterine rupture (aOR 2.21, 95% CI 1.31\u20133.74), transfusions (aOR 1.79, 95% CI 1.59\u20132.02), and congenital anomalies (aOR 2.35, 95% CI 2.01\u20132.75).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The ISF group experienced different complications than the post\u2010myomectomy group. Pregnancies post\u2010myomectomy could benefit from additional screening or interventions during pregnancy to reduce complications from malplacentation and ensure delivery in specialized centers to mitigate risks. Patients should be counseled regarding these potential risks. Increased understanding of the role of myomectomies on reproductive outcomes requires further prospective studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70211","type":"journal-article","created":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T10:49:09Z","timestamp":1747046949000},"page":"310-316","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Do myomectomies alter third\u2010trimester complications compared with women without myomectomies and uterine fibroids in\u00a0situ: A retrospective cohort study of an American population database"],"prefix":"10.1002","volume":"171","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4729-6986","authenticated-orcid":false,"given":"Perrine","family":"Ginod","sequence":"first","affiliation":[{"name":"MUHC Reproductive Centre McGill University  Montr\u00e9al Quebec Canada"},{"name":"CHU Dijon Bourgogne Service de Gyn\u00e9cologie\u2010Obst\u00e9trique et Assistance M\u00e9dicale \u00e0 la Procr\u00e9ation  Dijon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Badeghiesh","sequence":"additional","affiliation":[{"name":"Division of Gynecology and Obstetrics King Abdulaziz University, Rabigh Branch  Rabigh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitham","family":"Baghlaf","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Tabuk  Tabuk Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Dahan","sequence":"additional","affiliation":[{"name":"MUHC Reproductive Centre McGill University  Montr\u00e9al Quebec Canada"},{"name":"Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility McGill University  Montr\u00e9al Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181f7496d"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318197bbaf"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43032-021-00656-6"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.14343"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2020.01.003"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2017.06.034"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000196806.25897.7c"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004581"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2016.11.007"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.08.008"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2008.133702"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.07.008"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.05.077"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.1011311"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1101\/2024.03.05.24303824"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-024-06545-5"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14767"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.08.033"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep320"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2015.11.017"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.10.009"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2018.1542680"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.10.095"},{"key":"e_1_2_11_25_1","first-page":"1","article-title":"Update on overall prevalence of major birth defects\u2014Atlanta, Georgia, 1978\u20132005","volume":"57","author":"Centers for Disease Control and Prevention (CDC)","year":"2008","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_11_26_1","volume-title":"Complicating Conditions Associated with Childbirth, by Delivery Method and Payer, 2011. 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