{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:26:10Z","timestamp":1777483570308,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp;amp; Obste"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate the medical indications for termination of pregnancy, gestational age at termination, and methods used in our clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This observational retrospective study included pregnancy terminations after 10\u2009weeks of gestation for medical indications between 2010 and 2024. The indications were categorized into fetal, obstetric, and maternal groups. The mode of delivery and methods used for induction of labor were compared according to gestational age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 954 pregnancy terminations, 685 (71.81%) had fetal indications, 238 (24.95%) had obstetric indications, and 31 (3.24%) had maternal indications. A total of 149 (15.62%) were \u226524\u2009weeks of gestation. The median gestational age at termination in the maternal indication group was 14\u2009weeks, significantly lower than other groups (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). Central nervous system anomalies were the most prevalent indication for termination (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009298, 31.24%). The mode of delivery was vaginal in 96.43% of the patients. The requirement for additional methods of labor induction beyond misoprostol was significantly higher in pregnancies \u226524\u2009weeks of gestation (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Major fetal anomalies are the most common reason for pursuing termination of pregnancy, however, the relevance of obstetric and maternal considerations must also be acknowledged. Additional interventions to misoprostol may be required for induction of labor beyond 24\u2009week threshold.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70270","type":"journal-article","created":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T04:53:51Z","timestamp":1749012831000},"page":"1205-1211","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Termination of pregnancy for medical indications: A 14\u2010year analysis from a tertiary referral center"],"prefix":"10.1002","volume":"171","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2614-4411","authenticated-orcid":false,"given":"Yasemin","family":"Dogan","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Kocaeli University Faculty of Medicine  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1229-3888","authenticated-orcid":false,"given":"Semanur","family":"Karatas","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kocaeli University Faculty of Medicine  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8045-8369","authenticated-orcid":false,"given":"Mustafa An\u0131l","family":"Turhan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kocaeli University Faculty of Medicine  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9969-0448","authenticated-orcid":false,"given":"Ercan","family":"Kockaya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kocaeli University Faculty of Medicine  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2644-9338","authenticated-orcid":false,"given":"Muzeyyen Dilsad","family":"Eser","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kocaeli University Faculty of Medicine  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9103-4171","authenticated-orcid":false,"given":"Abdulkadir","family":"Babaoglu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kocaeli University Faculty of Medicine  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,4]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Center for Reproductive Rights.2024.The World\u2019s Abortion Laws. Accessed November 10 2024.https:\/\/www.reproductiverights.org\/maps\/worlds\u2010abortion\u2010laws\/"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-024-01673-0"},{"key":"e_1_2_10_4_1","unstructured":"National Legislative Bodies \/ National Authorities. Turkey: Law No. 2827 of 1983 Population Planning Law. 24 May 1983. 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