{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:45:44Z","timestamp":1786977944119,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004765","name":"Universiteit van die Vrystaat","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004765","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp;amp; Obste"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To test the feasibility and effectiveness of implementing the HemoClear microfiltration cell\u2010salvage system for cesarean sections in South Africa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a prospective experimental single\u2010arm feasibility study collecting and processing blood from 20 adult women undergoing cesarean section in Pelonomi Tertiary Hospital, Bloemfontein. Samples obtained from the blood salvaged during the cesarean section before (baseline) and after (concentrate and filtrate) the cell\u2010salvage procedure were tested for cellular, protein, electrolyte, and metabolic parameters, as well as blood coagulation and bacterial or amniotic fluid contamination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Median erythrocyte recovery using the HemoClear device was 75.5% (interquartile range [IQR], 63.8%\u201394.3%). An average volume of 826\u2009\u00b1\u2009146\u2009mL was processed in 15.3\u2009\u00b1\u20096.3\u2009min, resulting in 266\u2009\u00b1\u2009116\u2009mL of cell concentrate. The filtration procedure washed away &gt;75% of the \u03b1\u2010fetoprotein content in the concentrate, resulting in a median recovery of 24.0% (IQR, 21.4%\u201335.9%). Bacterial contamination was mostly consistent between baseline and concentrate for each patient and resulted mainly from normal skin flora. In six patients, nonskin species were detected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study shows the HemoClear system's adaptability to resource\u2010constrained environments, which opens the door for broader adoption of its use in similar resource\u2010constrained settings. The HemoClear cell\u2010salvage device is safe and efficient for intraoperative use in obstetric hemorrhage cases and can play an essential role in patient blood management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70313","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T06:34:55Z","timestamp":1750833295000},"page":"396-405","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Feasibility and effectiveness of the novel\n                    <scp>HemoClear<\/scp>\n                    microfiltration cell\u2010salvage system in cesarean sections in\u00a0South Africa"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2238-3251","authenticated-orcid":false,"given":"Nndwammbi C.","family":"Ramatsea","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology The University of the Free State  Bloemfontein South 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