{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T15:30:49Z","timestamp":1763825449825,"version":"3.45.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2025,12]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n To study the impact of updated international diagnostic criteria for follicle number per ovary (FNPO) on diagnosis of polycystic ovary syndrome (PCOS) and phenotype classification among Asian\u2010Indian women. Also, to compare the low FNPO and high FNPO groups in terms of clinical, anthropometric, endocrine, and metabolic parameters.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This was a cross\u2010sectional study conducted at a tertiary care referral center. Women aged 21\u201338\u2009years with a diagnosis of PCOS according to the 2003 Rotterdam criteria were included and were divided according to follicle number per ovary (FNPO) into low FNPO (12\u201319) and high FNPO (\u226520) groups.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 342 women with a diagnosis of\n PCOS<\/jats:styled-content>\n were included for analysis. Changing the\n FNPO<\/jats:styled-content>\n threshold to 20 or more led to reclassification of 18.49% (27\/146) of women from\n PCOS<\/jats:styled-content>\n phenotype A into phenotype B and excluded 37.75% (74\/196) of women from diagnosis of\n PCOS<\/jats:styled-content>\n (phenotypes C and D) to single criterion phenotypes. Although the high\n FNPO<\/jats:styled-content>\n group had a significantly higher number of participants with prolonged cycle length, higher luteinizing hormone\/follicle\u2010stimulating hormone ratio, higher modified Ferriman\u2010Gallwey score and higher serum anti\u2010M\u00fcllerian hormone levels, both groups had comparable anthropometric and metabolic parameters and comparable prevalence of metabolic syndrome. After excluding phenotype A (where diagnosis of\n PCOS<\/jats:styled-content>\n is otherwise not affected by\n FNPO<\/jats:styled-content>\n ), the cohort of phenotypes C and D was divided into the low and high\n FNPO<\/jats:styled-content>\n groups and both groups had comparable anthropometric and metabolic parameters and comparable incidence of metabolic syndrome.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Increasing the FNPO cut\u2010off of polycystic ovarian morphology excludes a significant number of women from the diagnosis of PCOS despite having comparable anthropometric and metabolic parameters. Robust data are required from different ethnic populations before the new cut\u2010off for polycystic ovarian morphology is accepted or refuted, especially in populations with a higher prevalence of non\u2010hyperandrogenic PCOS phenotypes.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ijgo.70316","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T08:15:23Z","timestamp":1750320923000},"page":"1400-1407","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of updated international diagnostic criteria for diagnosis of polycystic ovary syndrome (\n PCOS<\/scp>\n ) among Asian\u2010Indian women\u2014a cross\u2010sectional study"],"prefix":"10.1002","volume":"171","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4938-4466","authenticated-orcid":false,"given":"Reeta","family":"Mahey","sequence":"first","affiliation":[{"name":"Department of Obstetrics & Gynaecology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohitha","family":"Cheluvaraju","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynaecology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aarthi K.","family":"Jayraj","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynaecology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Rajput","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynaecology All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Upadhyay","sequence":"additional","affiliation":[{"name":"Department of Statistics All India Institute of Medical Sciences New Delhi 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