{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T08:14:07Z","timestamp":1771316047981,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T00:00:00Z","timestamp":1753056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T00:00:00Z","timestamp":1753056000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp;amp; Obste"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the prenatal ultrasound features of fetal ductal\u2010dependent congenital heart disease (DDCHD), analyze their association with chromosomal abnormalities, and summarize clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted on the clinical and ultrasound data of 308 fetuses diagnosed with DDCHD at our center over the past 10\u2009years. The ultrasound characteristics of each DDCHD type during early pregnancy were systematically summarized. Differences in the prevalence of abnormalities and pregnancy outcomes among various DDCHD types were statistically compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the first trimester, increased nuchal translucency showed a sensitivity of 60.7% (17\/28) and specificity of 100% (28\/28)\u00a0for DDCHD diagnosis. Distinctive features were consistently identified in the four\u2010chamber view and the three\u2010vessel tracheal view. The incidence of associated abnormalities differed significantly across DDCHD types. The systemic circulation\u2010dependent type showed the highest rate, followed by the pulmonary circulation\u2010dependent type, whereas the transposition of the great arteries with intact ventricular septum type had the lowest. Chromosomal abnormalities were observed less often in isolated DDCHD cases (5.3%, 1\/19) than in complex cases (34.1%, 14\/41) (\u00a0\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05). Overall live birth rate was 12.3% (38\/308), with no significant differences among subtypes. However, the timing of detection had a clear impact on live birth outcomes (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>First\u2010trimester ultrasound examination has diagnostic value for fetal DDCHD, identifying severe or complex cases. Second\u2010trimester ultrasound examination plays a vital role in the accurate identification and classification of fetal DDCHD. Complex DDCHD is associated with an increased risk of chromosomal abnormalities. Early identification and classification of DDCHD are critical to improving clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70367","type":"journal-article","created":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T10:44:35Z","timestamp":1753094675000},"page":"612-621","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prenatal ultrasound diagnosis and prognosis of ductal\u2010dependent congenital heart disease: A single\u2010center study in China"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2237-1378","authenticated-orcid":false,"given":"Yuanfu","family":"Ouyang","sequence":"first","affiliation":[{"name":"Department of Medical Ultrasonics Sanming Second Hospital  Yong'an Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Ling","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics &amp; Gynecology and Pediatrics Fujian Medical University  Fuzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronghua","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasonics Sanming Second Hospital  Yong'an Fujian China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiumei","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics &amp; Gynecology and Pediatrics Fujian Medical University  Fuzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guorong","family":"Lyu","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasonics Second Affiliated Hospital of Fujian Medical University  Quanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fa","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environmental Factors and Oncology, School of Public Health Fujian Medical University  Fuzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0992-9874","authenticated-orcid":false,"given":"Zongjie","family":"Weng","sequence":"additional","affiliation":[{"name":"Department of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics &amp; 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