{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:15:11Z","timestamp":1792080911771,"version":"4.4.0"},"reference-count":68,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp;amp; Obste"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cancer diagnoses in patients of reproductive age require balancing urgent oncological treatment with the need to preserve fertility. This FIGO Best Practice Advice outlines key considerations for fertility management in this population given the rising cancer incidence among young women and the reproductive risks posed by cancer treatments. The guidance evaluates the impact of chemotherapy, radiotherapy, surgery, and emerging therapies\u2014such as targeted agents and immunotherapies\u2014on gonadal function and fertility. Established fertility preservation methods, including oocyte\/embryo cryopreservation, sperm banking, and ovarian tissue freezing, are detailed alongside barriers to their adoption, such as cost and limited access. Early collaborative counseling with oncologists and fertility specialists is central to addressing timelines, psychological impacts, and priorities. Post\u2010treatment pathways, including assisted reproduction and surrogacy, are also explored. The guidance stresses the importance of integrating fertility\u2010sparing interventions and fertility preservation into cancer care while advocating for equitable access to resources. Further research is needed to refine preventive interventions, evaluate long\u2010term outcomes, and expand options for survivors globally. By prioritizing fertility preservation within oncological care, healthcare providers can better support the holistic needs of young individuals facing cancer.<\/jats:p>","DOI":"10.1002\/ijgo.70426","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T07:44:59Z","timestamp":1753947899000},"page":"32-44","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Cancer and fertility management:\n                    <scp>FIGO<\/scp>\n                    best practice advice"],"prefix":"10.1002","volume":"171","author":[{"given":"Nikhil","family":"Purandare","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0491-3187","authenticated-orcid":false,"given":"Francisco","family":"Ruiloba","sequence":"additional","affiliation":[{"name":"Fetal Medicine Research Unit King's College Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6450-0241","authenticated-orcid":false,"given":"Long","family":"Nguyen\u2010Hoang","sequence":"additional","affiliation":[{"name":"Fetal Medicine Centre Tam Anh HCMC General Hospital  Ho Chi Minh City Vietnam"},{"name":"Department of Obstetrics and Gynaecology Prince of Wales Hospital, Chinese University of Hong Kong  Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7288-494X","authenticated-orcid":false,"given":"Sarikapan","family":"Wilailak","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Ramathibodi Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nozomu","family":"Yanaihara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline P. W.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Prince of Wales Hospital, Chinese University of Hong Kong  Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaideep","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Rainbow IVF  Agra Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar","family":"Mocanu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Rotunda Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Amant","sequence":"additional","affiliation":[{"name":"Division of Gynecologic Oncology UZ Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orla","family":"McNally","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Royal Women's Hospital Melbourne, University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8665-9487","authenticated-orcid":false,"given":"Inge","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Woman's and Child Health and Public Health Sciences, Gynaecologic Oncology Unit Fondazione Policlinico Universitario Agostino Gemelli IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2598-8591","authenticated-orcid":false,"given":"Katie","family":"Flynn","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6427-114X","authenticated-orcid":false,"given":"Aya","family":"El Helali","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology Centre of Cancer Medicine, Hong Kong University  Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4734-1251","authenticated-orcid":false,"given":"Cynthia","family":"Maxwell","sequence":"additional","affiliation":[{"name":"Maternal Fetal Medicine Women's College Hospital and Mount Sinai Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8769-3273","authenticated-orcid":false,"given":"Sumaiya","family":"Adam","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology School of Medicine, Faculty of Health Sciences, University of Pretoria  Pretoria South Africa"},{"name":"Diabetes Research Centre, Faculty of Health Sciences University of Pretoria  Pretoria South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5202-9428","authenticated-orcid":false,"given":"Lina","family":"Bergman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3955-1304","authenticated-orcid":false,"given":"Surabhi","family":"Nanda","sequence":"additional","affiliation":[{"name":"Guy's and St Thomas NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie Tiempo","family":"Guinto","sequence":"additional","affiliation":[{"name":"University of the Philippines\u2010Philippine General Hospital  Manila Philippines"},{"name":"Department of Obstetrics and Gynecology Asian Hospital and Medical Center  Muntinlupa Philippines"},{"name":"St Luke's Medical Center\u2013Global City  Taguig Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3477-6494","authenticated-orcid":false,"given":"Fionnuala M.","family":"McAuliffe","sequence":"additional","affiliation":[{"name":"Perinatal Research Centre University College Dublin, National Maternity Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Nelson\u2010Piercy","sequence":"additional","affiliation":[{"name":"Division of Obstetric Medicine King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Nana","sequence":"additional","affiliation":[{"name":"Division of Obstetric Medicine King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kingston Health Sciences Centre, Queen's University  Kingston Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Berek","sequence":"additional","affiliation":[{"name":"Stanford Women's Cancer Center, Stanford Cancer Institute, Stanford University School of Medicine  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3547-6634","authenticated-orcid":false,"given":"Sharleen","family":"O'Reilly","sequence":"additional","affiliation":[{"name":"Perinatal Research Centre University College Dublin, National Maternity Hospital  Dublin Ireland"},{"name":"School of Agriculture and Food Science University College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pat","family":"O'Brien","sequence":"additional","affiliation":[{"name":"University College London Hospitals  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5079-2374","authenticated-orcid":false,"given":"Bo","family":"Jacobsson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg  Gothenburg Sweden"},{"name":"Department of Obstetrics and Gynaecology Region V\u00e4stra G\u00f6taland, Sahlgrenska University Hospital  Gothenburg Sweden"},{"name":"Department of Genetics and Bioinformatics, Division of Health Data and Digitalisation Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3944-4130","authenticated-orcid":false,"given":"Liona C.","family":"Poon","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Prince of Wales Hospital, Chinese University of Hong Kong  Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the FIGO Committee on the Impact of Pregnancy on Long\u2010term Health and the FIGO Division of Maternal and Newborn Health and in collaboration with the FIGO Committee on Women's Cancer and the FIGO Committee on Reproductive Medicine, Endocrinology and Infertility","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"e_1_2_17_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14102500"},{"key":"e_1_2_17_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(24)00523-0"},{"key":"e_1_2_17_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-024-01623-9"},{"key":"e_1_2_17_5_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21820"},{"key":"e_1_2_17_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO-24-02782"},{"key":"e_1_2_17_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2024.114010"},{"key":"e_1_2_17_8_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2016-0176"},{"key":"e_1_2_17_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-023-01388-z"},{"key":"e_1_2_17_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/482968"},{"key":"e_1_2_17_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16234005"},{"key":"e_1_2_17_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/jayao.2022.0055"},{"key":"e_1_2_17_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0000000000000185"},{"key":"e_1_2_17_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-015-0533-z"},{"key":"e_1_2_17_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2015.3251"},{"key":"e_1_2_17_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm6090089"},{"key":"e_1_2_17_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.15187"},{"key":"e_1_2_17_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.70138"},{"key":"e_1_2_17_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.21.1839"},{"key":"e_1_2_17_20_1","doi-asserted-by":"publisher","DOI":"10.5935\/1518-0557.20170011"},{"key":"e_1_2_17_21_1","first-page":"2069","article-title":"Public Awareness and Acceptability of PGT\u2010M in Cancer Predisposition Syndromes","volume":"14","author":"Calosci D","year":"2023","journal-title":"Gen"},{"key":"e_1_2_17_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-023-03552-3"},{"key":"e_1_2_17_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(24)00262-6"},{"key":"e_1_2_17_24_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.71.0582"},{"key":"e_1_2_17_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70251-1"},{"key":"e_1_2_17_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(16)00086-3"},{"key":"e_1_2_17_27_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-09-0287"},{"key":"e_1_2_17_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dey216"},{"key":"e_1_2_17_29_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.00535"},{"key":"e_1_2_17_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.70139"},{"key":"e_1_2_17_31_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.06.5888"},{"key":"e_1_2_17_32_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.49.2678"},{"key":"e_1_2_17_33_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2018.78.1914"},{"key":"e_1_2_17_34_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.22.8312"},{"key":"e_1_2_17_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.11.038"},{"key":"e_1_2_17_36_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-3180"},{"key":"e_1_2_17_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.695157"},{"key":"e_1_2_17_38_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.14588"},{"key":"e_1_2_17_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16025"},{"key":"e_1_2_17_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-019-01462-5"},{"key":"e_1_2_17_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.16185"},{"key":"e_1_2_17_42_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.59.3723"},{"key":"e_1_2_17_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deaa240"},{"key":"e_1_2_17_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-012-9912-x"},{"key":"e_1_2_17_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2020.08.011"},{"key":"e_1_2_17_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gore.2024.101337"},{"key":"e_1_2_17_47_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2024.1336047"},{"key":"e_1_2_17_48_1","doi-asserted-by":"publisher","DOI":"10.5732\/cjc.010.10529"},{"key":"e_1_2_17_49_1","doi-asserted-by":"publisher","DOI":"10.1080\/14737140.2017.1331130"},{"key":"e_1_2_17_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2023.11.015"},{"key":"e_1_2_17_51_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2024.0052"},{"key":"e_1_2_17_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.606335"},{"key":"e_1_2_17_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2020.06.034"},{"key":"e_1_2_17_54_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2021-002921"},{"key":"e_1_2_17_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2024.07.089"},{"key":"e_1_2_17_56_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2019-000398"},{"key":"e_1_2_17_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoac057"},{"key":"e_1_2_17_58_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmab041"},{"key":"e_1_2_17_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2024.02.020"},{"key":"e_1_2_17_60_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.01.159"},{"key":"e_1_2_17_61_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem362"},{"key":"e_1_2_17_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.31732"},{"key":"e_1_2_17_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28292"},{"key":"e_1_2_17_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.70258"},{"key":"e_1_2_17_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djac005"},{"key":"e_1_2_17_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(00)01802-1"},{"key":"e_1_2_17_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2023.08.467"},{"key":"e_1_2_17_68_1","doi-asserted-by":"publisher","DOI":"10.1200\/GO.19.00337"},{"key":"e_1_2_17_69_1","doi-asserted-by":"crossref","DOI":"10.1530\/RAF-24-0042","article-title":"Fertility care in low\u2010 and middle\u2010income countries","volume":"5","author":"Ombelet W","year":"2024","journal-title":"Reprod Fertil"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.70426","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.70426","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.70426","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T12:01:14Z","timestamp":1772971274000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.70426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,31]]},"references-count":68,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/ijgo.70426"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.70426","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,31]]},"assertion":[{"value":"2025-06-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}