{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:52:01Z","timestamp":1791179521610,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,8,16]],"date-time":"2025-08-16T00:00:00Z","timestamp":1755302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,16]],"date-time":"2025-08-16T00:00:00Z","timestamp":1755302400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the potential reciprocal influences between in\u00a0vitro fertilization (IVF) and the psychological states of patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A prospective cohort study involved 180 couples who sought consultation for IVF. To monitor the fluctuations in the emotional states of the couples throughout the IVF process, questionnaires were administered on two separate occasions: the first was conducted immediately before the initiation of medication, and the second was administered promptly following the completion of embryo transfer. The BECK inventories for anxiety and depression were employed for evaluation. Pregnancy outcomes were exclusively analyzed for women who received high\u2010quality blastocysts, with cleavage\u2010stage embryo transfers being excluded from consideration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Pregnancy rates did not significantly differ based on the presence of heightened anxiety and\/or depression among couples. Notably, a correlation was identified between severe anxiety in women before IVF and diminished rates of fertilization, as well as lower blastocyst\/oocyte and blastocyst\/metaphase II (M2) ratios (8.7\u2009\u00b1\u20095.0 vs. 7.5\u2009\u00b1\u20096.1,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.029; 0.284\u2009\u00b1\u20090.199 vs. 0.218\u2009\u00b1\u20090.209,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001; and 0.333\u2009\u00b1\u20090.209 vs. 0.272\u2009\u00b1\u20090.232,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.016, respectively). In the male cohort, elevated anxiety scores, either pre\u2010 or post\u2010IVF treatment, were found to be linked with a reduced mean oocyte count, as well as lower rates of M2, fertilization, blastocyst, and total embryo counts (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pregnancy rates were not affected by the presence of anxiety and depression, as they do not exert a significant impact on the implantation success of blastocysts. However, given that fertilization rates are statistically diminished in instances of severe anxiety, which consequently results in a reduced number of blastocysts and total embryos, a decline in cumulative pregnancy rates may be anticipated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70466","type":"journal-article","created":{"date-parts":[[2025,8,16]],"date-time":"2025-08-16T08:10:41Z","timestamp":1755331841000},"page":"1221-1237","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A pilot investigation on possible interactions between clinical parameters and the psychology of couples undergoing\n                    <scp>IVF<\/scp>"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5638-3675","authenticated-orcid":false,"given":"Gercek","family":"Aydin","sequence":"first","affiliation":[{"name":"Bursa Eurofertil IVF Center  Bursa Turkey"},{"name":"Faculty of Medicine, Department of Obstetrics &amp; Gynecology Istanbul Health and Technology University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5695-2586","authenticated-orcid":false,"given":"Mehmet","family":"Bulbul","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Obstetrics &amp; Gynecology Bulent Ecevit University  Zonguldak Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4926-825X","authenticated-orcid":false,"given":"Elif","family":"Ergin","sequence":"additional","affiliation":[{"name":"Bursa Eurofertil IVF Center  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Gul","family":"Aydin","sequence":"additional","affiliation":[{"name":"Private Psychiatry Clinic  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9049-2413","authenticated-orcid":false,"given":"Cengiz","family":"Akkaya","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Psychiatry Uludag University  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8859-0639","authenticated-orcid":false,"given":"Safak","family":"Hatirnaz","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Kent University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8426-8490","authenticated-orcid":false,"given":"Andrea","family":"Tinelli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology CERICSAL (CEntro di RIcerca Clinico SALentino), \u201cVeris Delli Ponti Hospital\u201d  Scorrano 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