{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:52:00Z","timestamp":1791179520652,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2026,2]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n We conducted a comparative retrospective bicentric study of rectal endometriosis treatment with high\u2010intensity focused ultrasound (HIFU) and surgery in terms of symptoms and treatment\u2010related morbidity at 6\u2009months.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n All patients with a single symptomatic rectal nodule who had failed hormonal treatment were included in the present study. Patients' symptomatology was assessed using questionnaires: gynecologic and digestive symptoms (visual analog scale [VAS]), health status (MOSSF\u201036), fecal incontinence (Wexner), constipation (Knowles Eccersley Scott Symptom [KESS] score) and overall sexual health (FSFI). We also assessed the morbidity according to the Clavien\u2013Dindo classification.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 120 patients, 60 in each group, received HIFU or rectal surgery. The characteristics of rectal nodules were similar in both groups. In the HIFU and surgery groups, Clavien\u2013Dindo grades 2 and 3 complication rates were 3.3% versus 21.7% (\n P<\/jats:italic>\n \u2009=\u20090.002) and 0% versus 10% (\n P<\/jats:italic>\n \u2009=\u20090.01), respectively. Hospitalization duration was also significantly shorter for the HIFU group (1 vs 3\u2009days;\n P<\/jats:italic>\n \u2009<\u20090.001). In the HIFU group, significant improvement was observed in acute pelvic pain\/dysmenorrhea (\n P<\/jats:italic>\n \u2009<\u20090.001), dyspareunia (\n P<\/jats:italic>\n \u2009<\u20090.001), diarrhea (\n P<\/jats:italic>\n \u2009<\u20090.001), tenesmus\/spasms (\n P<\/jats:italic>\n \u2009<\u20090.001), pain on defecation (\n P<\/jats:italic>\n \u2009<\u20090.001), and urinary urgency (\n P<\/jats:italic>\n \u2009<\u20090.026). In the surgical arm, significant improvement was observed in acute pelvic pain\/dysmenorrhea (\n P<\/jats:italic>\n \u2009<\u20090.017), diarrhea (\n P<\/jats:italic>\n \u2009<\u20090.002), tenesmus\/spasms (\n P<\/jats:italic>\n \u2009<\u20090.001), and pain on defecation (\n P<\/jats:italic>\n \u2009<\u20090.002). In both groups, an improvement in FSFI, KESS, and Wexner scores and health status was noted at 6\u2009months.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n In selected patients with only one rectal location, HIFU treatment enables a similar symptom\u2010related and quality\u2010of\u2010life outcome with a significant reduction in the risk of postoperative complications.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ijgo.70478","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T04:54:11Z","timestamp":1755838451000},"page":"1245-1254","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of rectal endometriosis treatment with high\u2010intensity focused ultrasound versus surgery: A clinical retrospective multicenter trial"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3455-9908","authenticated-orcid":false,"given":"Gil","family":"Dubernard","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics Croix\u2010Rousse University Hospital, Hospices Civils de Lyon Lyon France"},{"name":"Laboratory of Therapeutic Applications of Ultrasound Claude Bernard University Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chlo\u00e9","family":"Devantay","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Croix\u2010Rousse University Hospital, Hospices Civils de Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9847-2564","authenticated-orcid":false,"given":"Charles\u2010Andr\u00e9","family":"Philip","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Croix\u2010Rousse University Hospital, Hospices Civils de Lyon Lyon France"},{"name":"Laboratory of Therapeutic Applications of Ultrasound Claude Bernard University Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Warembourg","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Croix\u2010Rousse University Hospital, Hospices Civils de Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Nguyen\u2010Ba","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Croix\u2010Rousse University Hospital, Hospices Civils de Lyon Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9283-5723","authenticated-orcid":false,"given":"Thomas","family":"Dennis","sequence":"additional","affiliation":[{"name":"Franco\u2010European Multidisciplinary Endometriosis Institute (IFEM Endo), Clinique Tivoli\u2010Ducos Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Merlot","sequence":"additional","affiliation":[{"name":"Franco\u2010European Multidisciplinary Endometriosis Institute (IFEM Endo), Clinique Tivoli\u2010Ducos Bordeaux France"},{"name":"Franco\u2010European Multidisciplinary Endometriosis Institute Middle East Clinic Burjeel Medical City Abu Dhabi United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9237-0628","authenticated-orcid":false,"given":"Horace","family":"Roman","sequence":"additional","affiliation":[{"name":"Franco\u2010European Multidisciplinary Endometriosis Institute (IFEM Endo), Clinique Tivoli\u2010Ducos Bordeaux France"},{"name":"Franco\u2010European Multidisciplinary Endometriosis Institute Middle East Clinic Burjeel Medical City Abu Dhabi United Arab Emirates"},{"name":"Department of Gynecology and Obstetrics Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1810764"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2020.06.004"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.10.022"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/09513590.2024.2336121"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.09.023"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17497"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.21937"},{"key":"e_1_2_9_9_1","first-page":"1673","article-title":"Evaluating the safety of high\u2010intensity focused ultrasound treatment for rectal endometriosis: results from a French prospective multicentre study including 60 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