{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:51:39Z","timestamp":1791179499456,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study reviews the outcome of a series of hysteroscopic adhesiolysis (HA) in an outpatient setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This is a retrospective case series study performed at a fertility center. A total of 1073 women with mild, moderate, or severe intrauterine adhesions (IUAs) underwent HA between January 2011 and December 2023. Fourteen women who underwent HA under regional or general anesthesia were excluded. The remaining 1059 women were scheduled for HA in an outpatient setting under conscious sedation and local anesthesia. At the end of the HA procedure, within 1\u2009min, the severity of discomfort or pain was assessed using the visual analogue scale (VAS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Hysteroscopic adhesiolysis was successfully performed under conscious sedation and local anesthesia in 1051 (97.9%) women during the study period. The mean age of the participants was 38.2\u2009\u00b1\u20095.25\u2009years. The mean VAS score was 1.46\u2009\u00b1\u20091.18. In women with mild, moderate, and severe IUAs, the scores were 0.77, 1.42, and 2.49, respectively. In nine (0.9%) women, a uterine perforation occurred. Of the 618 (58.8%) women with complete follow\u2010up, 140 (27.7%) conceived. In women with mild, moderate, and severe IUAs, the miscarriage rates were, respectively, 15.9%, 19.0%, and 60%. The live birth rates were 16.9%, 9.5%, and 1.4%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hysteroscopic adhesiolysis in an outpatient setting under conscious sedation and local anesthesia appears feasible and is well tolerated, with a low complication rate. Given the retrospective nature of the study, the results should be interpreted with caution. Future studies are needed to evaluate HA under conscious sedation and local anesthesia, including long\u2010term fertility and reproductive outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70486","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T10:12:27Z","timestamp":1755684747000},"page":"1238-1244","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hysteroscopic adhesiolysis under conscious sedation and local anesthesia in an outpatient setting: A large retrospective study"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2536-4874","authenticated-orcid":false,"given":"Jude E.","family":"Okohue","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Gynescope Specialist Hospital and Madonna University Teaching Hospital  Port Harcourt Rivers State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo B.","family":"Hooker","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Zaans Medical Center  Zaandam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose \u201cTony\u201d","family":"Carugno","sequence":"additional","affiliation":[{"name":"Obstetrics, Gynecology and Reproductive Sciences Department, Division of Minimally Invasive Gynecology University of Miami, Miller School of Medicine  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bolarinde","family":"Ola","sequence":"additional","affiliation":[{"name":"Department of Reproductive and Developmental Medicine Sheffield Teaching Hospital NHS, Foundation Trust, Jessop Wing  Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.09.036"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1948.tb07045.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.02.096"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmt045"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/GMIT.GMIT_11_19"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1272470"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2013.08.018"},{"key":"e_1_2_10_9_1","first-page":"90","article-title":"Severity of intrauterine adhesions and pregnancy success rates after treatment: comparison of adhesions obtained from open myomectomy versus uterine curettage","volume":"26","author":"Okohue JE","year":"2022","journal-title":"Afr J Reprod Health"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S165474"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2014.12.006"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.06.034"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1472-6483(10)61108-X"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2017.08.009"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02503.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.1997.tb02254.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(78)90322-8"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)46268-0"},{"key":"e_1_2_10_19_1","doi-asserted-by":"crossref","unstructured":"EnabudosoEJ GharoroEP AndeABA EkpeUP OkohueEJ.Five\u2010year review of complicated induced abortions in University of Benin Teaching Hospital Benin City.2007;9:13\u201021.","DOI":"10.4314\/bjpm.v9i1.47368"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/0300-1652.86139"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2021.01.028"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58081132"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10397-015-0895-3"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-020-05885-9"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-003-9144-3"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-022-05164-2"}],"container-title":["International Journal of Gynecology &amp; 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