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Pregnancies involving uterine fibroids are generally uncomplicated. However, complications can occur, particularly in cases of multiple fibroids, when the fibroids are larger than 5\u2009cm, or when they are located in the lower uterine segment. Between 10% and 30% of pregnant women with fibroids experience complications during pregnancy, labor, and the postpartum period. The most common complication during pregnancy, which can occur in 8% of women, is red degeneration. High\u2010quality data on the relationship between fibroids and pregnancy outcome are very limited. Potential obstetric complications include preterm birth (increased risk, OR 1.5; 95% CI, 1.3\u20131.7), malpresentation of the baby (OR 2.65; 95% CI, 1.60\u20133.70), placental abruption (OR 2.63; 95% CI, 1.38\u20133.88), placenta previa (OR 2.21; 95% CI, 1.48\u20132.94), cesarean birth (OR 2.60; 95% CI, 2.02\u20133.18), postpartum hemorrhage (OR 2.95; 95% CI, 1.86\u20134.66), and other rare occurrences. Most women with uterine fibroids are able to deliver vaginally without complications. Cesarean birth is typically performed for standard obstetric indications. It is recommended that cesarean myomectomy should be avoided when possible.<\/jats:p>","DOI":"10.1002\/ijgo.70612","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T10:49:11Z","timestamp":1762426151000},"page":"51-58","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Fibroids and pregnancy"],"prefix":"10.1002","volume":"172","author":[{"given":"Diana","family":"Ramasauskaite","sequence":"first","affiliation":[{"name":"Clinic of Obstetrics and Gynecology Vilnius University Faculty of Medicine  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil","family":"Purandare","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology University College Hospital Galway, University of Galway  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivonne","family":"Diaz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Nueva Granada and Unisanitas University  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta","family":"Kvederaite\u2010Budre","sequence":"additional","affiliation":[{"name":"Clinic of Obstetrics and Gynecology Vilnius University Faculty of Medicine  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Titus K.","family":"Beyuo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology University of Ghana Medical School  Accra Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolly","family":"Beyeza\u2010Kashesya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Mulago Specialised Women and Neonatal Hospital  Kampala Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Jacobsson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Sahlgrenska Academy, University of Gothenburg  Gothenburg Sweden"},{"name":"Department of Obstetrics and Gynecology Sahlgrenska University Hospital  Gothenburg Region V\u00e4stra G\u00f6taland Sweden"},{"name":"Department of Genetics and Bioinformatics, Division of Health Data and Digitalisation Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,6]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181f7496d"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2022.06.028"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2010.11.011"},{"issue":"1","key":"e_1_2_14_5_1","article-title":"Surgical treatment of fibroids for subfertility","volume":"1","author":"Metwally M","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2017.06.034"},{"key":"e_1_2_14_7_1","unstructured":"StewartEA.Uterine fibroids (leiomyomas): treatment overview. 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