{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:47:13Z","timestamp":1777870033594,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100010731","name":"Faculty of Medicine, Chiang Mai University","doi-asserted-by":"publisher","award":["123\/2567"],"award-info":[{"award-number":["123\/2567"]}],"id":[{"id":"10.13039\/501100010731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluates the performance of third\u2010trimester screening for late\u2010onset pregnancy\u2010induced hypertension (PIH) using the Fetal Medicine Foundation (FMF) prediction model and compares its diagnostic accuracy with locally developed Thai predictive models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective diagnostic accuracy study was conducted in singleton normotensive pregnancies. Mean arterial pressure (MAP), uterine artery pulsatility index (UtPI), and placental growth factor (PlGF) were measured between 30 and 34\u2009weeks. The primary outcome was the development of PIH. The diagnostic performances of each marker, and their combinations, were evaluated using both the FMF model and Thai models specifically derived from this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 213 participants meeting the inclusion criteria, 18 (8.45%) developed PIH. Based on the FMF model, MAP, UtPI, and PlGF yielded areas under curve (AUCs) of 0.827, 0.631, and 0.857, respectively. The combination of MAP and PlGF achieved the highest AUC of 0.890, with a sensitivity of 66.7% at a 10% false\u2010positive rate, better than 55.7 and 44.4% provided by PlGF alone and MAP alone, respectively. Although UtPI alone demonstrated significant predictive value, it did not provide additional benefit when combined with other markers. Thai predictive models developed from the same dataset showed diagnostic performance comparable to that of the FMF model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The FMF model for predicting PIH, using the combination of PlGF and MAP in the early third trimester, demonstrated better diagnostic performance than MAP alone. This finding suggests that the FMF algorithm can be applied to the Thai population, although its performance is not as robust as that reported in Western populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70645","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T07:59:26Z","timestamp":1763193566000},"page":"731-740","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Performance of the Fetal Medicine Foundation model in the third trimester for predicting late\u2010onset pregnancy\u2010induced hypertension among Thai pregnant women"],"prefix":"10.1002","volume":"173","author":[{"given":"Parada","family":"Wangtragoolchai","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4838-175X","authenticated-orcid":false,"given":"Suchaya","family":"Luewan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"},{"name":"Fetal Center, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theera","family":"Tongsong","sequence":"additional","affiliation":[{"name":"Fetal Center, Faculty of Medicine Chiang Mai University  Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003891"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.18095"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2023.04.039"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13041022"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.57828"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.18211"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2023.12.031"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767050902994754"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.127977"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.11.002"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1517\/17530059.2012.659726"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1704559"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15812"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.02.016"},{"key":"e_1_2_11_16_1","unstructured":"The Fetal Medicine Foundation.Risk assessment: Risk preeclampsia. Accessed June 3 2025.https:\/\/fetalmedicine.org\/research\/assess\/preeclampsia\/third\u2010trimester."},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2023.03.032"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26092"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2014.02.013"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.2307\/2531595"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.19111"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.70645","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.70645","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.70645","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:13:13Z","timestamp":1777561993000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.70645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,14]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/ijgo.70645"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.70645","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,14]]},"assertion":[{"value":"2025-07-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}