{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T15:12:13Z","timestamp":1776093133616,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2026,4]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n To determine delivery outcomes in women diagnosed with prelabor rupture of membranes (PROM) who required re\u2010amniotomy.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This retrospective cohort study included 24\u2009966 women with PROM at a single university\u2010affiliated tertiary medical center (2011\u20132023). Labor outcome was compared between women requiring re\u2010amniotomy during delivery and those who did not. The primary outcome was the rate of cesarean delivery (CD). Secondary outcomes were maternal obstetric complications, including assisted operative vaginal delivery, intrapartum fever, postpartum hemorrhage, need for blood products transfusion and need for re\u2010admission within 30\u2009days postpartum.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Re\u2010amniotomy was required in 5.5% (\n n<\/jats:italic>\n \u2009=\u20091364) of cases and was associated with higher CD rates (10.2% versus 5.6%,\n P<\/jats:italic>\n \u2009<\u20090.001). In the adjusted analysis controlling for significant confounders identified in univariate analysis, re\u2010amniotomy remained independently associated with increased risk for CD (adjusted odds ratio 1.452, 95% confidence interval 1.010\u20132.080,\n P<\/jats:italic>\n \u2009=\u20090.043). For secondary maternal obstetric outcomes (assisted vaginal delivery, intrapartum fever, and postpartum hemorrhage), no independent associations with re\u2010amniotomy were found after multivariate adjustment. Women requiring re\u2010amniotomy had significantly longer intervals from PROM to delivery (26:49\u2009\u00b1\u200919:52 vs. 18:36\u2009\u00b1\u200914:34\u2009h:min,\n P<\/jats:italic>\n \u2009<\u20090.001) and lower rates of achieving active labor within 24\u2009h (62.3% vs. 74.2%,\n P<\/jats:italic>\n \u2009<\u20090.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The need for re\u2010amniotomy during delivery in women with PROM is associated with an increased risk for CD and prolonged labor.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ijgo.70646","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T11:41:38Z","timestamp":1762861298000},"page":"498-505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of re\u2010amniotomy in prelabor rupture of membranes at term and increased risk of cesarean delivery"],"prefix":"10.1002","volume":"173","author":[{"given":"Roza","family":"Berkovitz\u2010Shperling","sequence":"first","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center Gray Faculty of Medicine and Health Science, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roni","family":"Berin","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center Gray Faculty of Medicine and Health Science, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Gabbai","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center Gray Faculty of Medicine and Health Science, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yariv","family":"Yogev","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center Gray Faculty of Medicine and Health Science, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shai","family":"Ram","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center Gray Faculty of Medicine and Health Science, Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003700"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199604183341601"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)34525-X"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(51)91163"},{"key":"e_1_2_10_6_1","volume-title":"The Principles and Practice of Obstetrics","author":"DeLee JB","year":"1947"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.15851"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003668"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002455"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005302.pub3"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.09.035"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002343"}],"container-title":["International Journal of Gynecology & Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.70646","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.70646","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.70646","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T14:24:24Z","timestamp":1776090264000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.70646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,11]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/ijgo.70646"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.70646","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,11]]},"assertion":[{"value":"2025-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}