{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:47:15Z","timestamp":1777870035264,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate whether expectant management of late preterm prelabor rupture of membranes (PPROM) in patients colonized with Group B streptococcus (GBS) is associated with an increased risk of adverse maternal and neonatal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>\n                      This cohort study analyzed data from singleton pregnancies complicated by late PPROM between 34\n                      <jats:sup>+0<\/jats:sup>\n                      and 36\n                      <jats:sup>+6<\/jats:sup>\n                      weeks of pregnancy, where a documented GBS rectovaginal culture result was available, and who underwent expectant management until 37\n                      <jats:sup>+0<\/jats:sup>\n                      weeks. After rectovaginal GBS swabs were taken, patients received an ampicillin\u2010based regimen: this was discontinued if swab results were GBS\u2010negative or continued for 1\u2009week if GBS\u2010positive. Outcomes of patients with a positive GBS culture were compared with those with a negative culture. The primary outcomes were chorioamnionitis and neonatal fever. Secondary outcomes included the mode of delivery, latency from PPROM to delivery, placental abruption, neonatal intensive care unit admission, and early\u2010onset neonatal GBS bacteremia, as well as composite adverse maternal and neonatal outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 217 patients met the inclusion criteria for this study. Among these, 98 (45.2%) were identified as GBS carriers, and 119 (54.8%) were noncarriers. Baseline characteristics were comparable between the two groups. There was no significant difference in the rates of chorioamnionitis (2.1% versus 0.5%\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.23), neonatal fever (2.1% versus 1.7%\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.42) latency from PPROM to delivery and adverse maternal or neonatal outcomes between GBS carriers and noncarriers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Expectant management of GBS\u2010colonized women with late PPROM, when accompanied by appropriate antibiotic prophylaxis and close maternal\u2010fetal surveillance is not significantly associated with adverse outcomes and appears to be a safe option. These findings reinforce the need for evidence\u2010based, individualized management strategies for GBS colonization in late PPROM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70684","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T11:29:48Z","timestamp":1763983788000},"page":"876-882","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Is expectant management of late preterm prelabor rupture of membranes an option in patients with Group B streptococcus colonization?"],"prefix":"10.1002","volume":"173","author":[{"given":"Elior","family":"Eliasi","sequence":"first","affiliation":[{"name":"Ma'ayanei Hayeshua Medical Center  Bnei Brak Israel"},{"name":"School of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabina","family":"Razdolsky","sequence":"additional","affiliation":[{"name":"Ma'ayanei Hayeshua Medical Center  Bnei Brak Israel"},{"name":"School of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Minich","sequence":"additional","affiliation":[{"name":"Ma'ayanei Hayeshua Medical Center  Bnei Brak Israel"},{"name":"School of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanny","family":"Kolp Asis","sequence":"additional","affiliation":[{"name":"Ma'ayanei Hayeshua Medical Center  Bnei Brak Israel"},{"name":"School of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ella","family":"Segal","sequence":"additional","affiliation":[{"name":"School of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Sheba Medical Center Tel Hashomer  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariel","family":"Many","sequence":"additional","affiliation":[{"name":"Ma'ayanei Hayeshua Medical Center  Bnei Brak Israel"},{"name":"School of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5304-2296","authenticated-orcid":false,"given":"Miriam","family":"Lopian","sequence":"additional","affiliation":[{"name":"Ma'ayanei Hayeshua Medical Center  Bnei Brak Israel"},{"name":"School of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-046046"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.106766"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/145.1.1"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.03010.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2024.02.015"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.17114"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2014.990432"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00724-2"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2024.101563"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix658"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181acf6bd"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2217"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318223bad2"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1542\/pir.2023-006154"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.07.024"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12889"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2019.02.021"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.15803"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004142"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2005.00389.x"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/4823404"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-2282-9072"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogc.2017.06.003"},{"issue":"1","key":"e_1_2_9_25_1","first-page":"1","article-title":"Prevention of group B streptococcal early\u2010onset disease in newborns: ACOG Committee opinion summary, number 782","volume":"134","year":"2019","journal-title":"Obstet Gynecol"}],"container-title":["International Journal of Gynecology &amp; 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