{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T19:55:30Z","timestamp":1781812530776,"version":"3.54.5"},"reference-count":87,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Uterine leiomyomas are benign gynecologic tumors that occur in approximately 80% of women of reproductive age. Although often asymptomatic, these tumors may, in some cases, require gynecologic intervention. Conventional imaging tools, such as ultrasonography (US) and magnetic resonance imaging (MRI), are most commonly used to guide treatment selection. However, none of these methods provides definitive criteria for qualifying patients for medical, non\u2010invasive, or surgical therapy. Therefore, there is a pressing need to develop innovative tools that improve the evaluation of uterine masses and allow for safer and more effective patient stratification for appropriate treatment options. In this context, the relatively recent development of techniques for assessing tissue stiffness offers promising possibilities. The aim of this review was to analyze available research on the use of ultrasound elastography and magnetic resonance elastography in the evaluation of uterine leiomyomas. It highlights the feasibility of these techniques in assessing the viscoelastic properties of leiomyomas and explores their potential application in differential diagnosis and treatment planning.<\/jats:p>","DOI":"10.1002\/ijgo.70809","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T09:03:56Z","timestamp":1768554236000},"page":"50-61","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of tissue stiffness: A deeper insight into the nature of uterine leiomyomas and its possible clinical applications"],"prefix":"10.1002","volume":"174","author":[{"given":"Bogdan","family":"Obrzut","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine University of Rzesz\u00f3w  Rzesz\u00f3w Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0715-9578","authenticated-orcid":false,"given":"Vitaliy","family":"Atamaniuk","sequence":"additional","affiliation":[{"name":"Department of Physics and Medical Engineering, Faculty of Mathematics and Applied Physics Rzesz\u00f3w University of Technology  Rzesz\u00f3w Poland"},{"name":"Department of Radiology Independent Public Health Care Center of the Ministry of Interior and Administration in Rzesz\u00f3w  Rzesz\u00f3w Poland"},{"name":"Laboratory of Innovative Medical Imaging Methods, Faculty of Health Sciences and Psychology, Medical College University of Rzesz\u00f3w  Rzesz\u00f3w Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danuta","family":"Vasilevska","sequence":"additional","affiliation":[{"name":"Department of Gynecology Vilnius University Hospital \u201cSantaros Klinikos\u201d  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0141ukasz","family":"Ha\u0144czyk","sequence":"additional","affiliation":[{"name":"Department of Radiology Independent Public Health Care Center of the Ministry of Interior and Administration in Rzesz\u00f3w  Rzesz\u00f3w Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzanna","family":"Obrzut","sequence":"additional","affiliation":[{"name":"Laboratory of Innovative Medical Imaging Methods, Faculty of Health Sciences and Psychology, Medical College University of Rzesz\u00f3w  Rzesz\u00f3w Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,16]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43032-022-00877-3"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogrm.2013.02.001"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2013.02.017"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmt058"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogrm.2020.02.001"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2010.05.012"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.01.051"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1411029"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2022.2039788"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.06.051"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13102"},{"key":"e_1_2_13_13_1","article-title":"Uterine artery embolization for symptomatic uterine fibroids","volume":"12","author":"Gupta JK","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.47102\/annals-acadmedsg.V43N11p550"},{"issue":"1","key":"e_1_2_13_15_1","first-page":"656","article-title":"Efficacy and safety of magnetic resonance\u2010guided focused ultrasound surgery (MRgFUS) ablation in the management of abnormal uterine bleeding due to uterine leiomyoma or adenomyosis","volume":"14","author":"Huang Y","year":"2022","journal-title":"Am J Transl Res"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2015.11.016"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2020.1754390"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2023.2205581"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.12.037"},{"issue":"179","key":"e_1_2_13_20_1","first-page":"e1","article-title":"Incidence of sarcoma in patients undergoing hysterectomy for benign indications: a population\u2010based study","volume":"220","author":"Multinu F","year":"2019","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_13_21_1","first-page":"414","article-title":"Uterine sarcoma in patients operated on for presumed leiomyoma and rapidly growing leiomyoma","volume":"83","author":"Parker WH","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2012.07.080"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0050058"},{"key":"e_1_2_13_24_1","unstructured":"Food and Drug Administration.Quantitative assessment of the prevalence of unsuspected uterine sarcoma in women undergoing treatment of uterine fibroids: summary and key findings.2014.https:\/\/fda.report\/media\/88703\/Quantitative\u2010Assessment\u2010of\u2010the\u2010Prevalence\u2010of\u2010Unsuspected\u2010Uterine\u2010Sarcoma\u2010in\u2010Women\u2010Undergoing\u2010Treatment\u2010of\u2010Uterine\u2010Fibroids\u2010\u2010\u2010Summary\u2010and\u2010Key\u2010Findings.pdf\/"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2011.01.014"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2010.07.001"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.01126.x"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2013.11.024"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2005.00397.x"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28844"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.04.021"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/IGC.0b013e31819a1f8f"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1438.2002.01086.x"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)91298-Q"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20207"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2015.11.014"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/20363613251327080"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-2378-6926"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.18650"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.4103\/eus-d-21-00151"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2013.01.022"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jeud.2023.100014"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13942"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.15149"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18042026"},{"key":"e_1_2_13_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-02498-3"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.2147\/ijgm.S312292"},{"key":"e_1_2_13_48_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2020.11759"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.15630"},{"issue":"4","key":"e_1_2_13_50_1","first-page":"373","article-title":"Importance of Transvaginal Elastography in the Diagnosis of Uterine Fibroids and Adenomyosis","volume":"37","author":"Frank ML","year":"2016","journal-title":"Ultraschall Med"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12519"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719117750752"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11080824"},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11133757"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14676"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.22074\/ijfs.2021.523075.1074"},{"key":"e_1_2_13_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2020.102002"},{"key":"e_1_2_13_58_1","doi-asserted-by":"publisher","DOI":"10.3906\/sag-1908-171"},{"key":"e_1_2_13_59_1","doi-asserted-by":"publisher","DOI":"10.2217\/iim.11.41"},{"key":"e_1_2_13_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2015.03.007"},{"key":"e_1_2_13_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmb2.12404"},{"key":"e_1_2_13_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2015.03.009"},{"key":"e_1_2_13_63_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.03.076"},{"key":"e_1_2_13_64_1","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.11.291"},{"key":"e_1_2_13_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22723"},{"key":"e_1_2_13_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24147"},{"key":"e_1_2_13_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-2978-8"},{"key":"e_1_2_13_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-012-2474-6"},{"key":"e_1_2_13_69_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.3123"},{"key":"e_1_2_13_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24028"},{"key":"e_1_2_13_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22610"},{"key":"e_1_2_13_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22670"},{"key":"e_1_2_13_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24268"},{"key":"e_1_2_13_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24572"},{"key":"e_1_2_13_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-75\u2009806-2"},{"key":"e_1_2_13_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2024.06.005"},{"key":"e_1_2_13_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-014-0315-6"},{"key":"e_1_2_13_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.06.004"},{"key":"e_1_2_13_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-017-1314-1"},{"key":"e_1_2_13_80_1","doi-asserted-by":"publisher","DOI":"10.5603\/GP.a2020.0067"},{"key":"e_1_2_13_81_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-014-3305-8"},{"key":"e_1_2_13_82_1","doi-asserted-by":"publisher","DOI":"10.1177\/016173469802000403"},{"issue":"11","key":"e_1_2_13_83_1","first-page":"1001","article-title":"Diagnostic criteria for uterine smooth muscle tumors: leiomyoma variants associated with malignant behavior","volume":"52","author":"Giuntoli RL","year":"2007","journal-title":"J Reprod Med"},{"key":"e_1_2_13_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.03.018"},{"key":"e_1_2_13_85_1","doi-asserted-by":"publisher","DOI":"10.5603\/GP.2020.0034"},{"key":"e_1_2_13_86_1","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.tn.2017-0103"},{"key":"e_1_2_13_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.12.016"},{"key":"e_1_2_13_88_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-017-1340-z"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.70809","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.70809","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.70809","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T19:06:26Z","timestamp":1781809586000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.70809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,16]]},"references-count":87,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/ijgo.70809"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.70809","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,16]]},"assertion":[{"value":"2025-10-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}