{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T19:55:35Z","timestamp":1781812535935,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To develop a three\u2010dimensional (3D) deep\u2010learning radiomics from magnetic resonance\u2010T2\u2010weighted imaging (T2WI) for predicting the risk of placenta accreta spectrum (PAS) disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study conducted a retrospective multicenter involving 601 suspected PAS cases. Center A contributed 476 cases, while Centers B and C provided 63\/62 cases. The Center A and Center B (totaling 539 cases) served as the data sources for model training and internal validation, and were divided into a training set (377 cases) and a validation set (162 cases) using the stratified random sampling method. The 62 cases from Center C were designated as the independent external test set. All patients underwent magnetic resonance imaging (MRI), with sagittal T2WI acquired. Clinical features predictive of PAS were identified using univariate and multivariate logistic regression analyses. Radiologist diagnosis was performed by radiologists of varying levels of experience. Radiomics features were extracted from the T2WI scans. Volumetric features were derived from the entire 3D regions of interest on T2WI images. Deep features were subsequently extracted using a pretrained 3D ResNet50\/DenseNet121\/ShuffleNet model, enhanced via transfer learning. Key predictive features were selected using correlation filtering and Lasso regression, culminating in a 3D radiomics signature. Model performance was evaluated on the independent validation cohort using receiver operating characteristic (ROC) curve analysis, with area under the curve (AUC) comparisons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The 3D deep learning (DL3D) model (single\u2010modality) achieved the highest performance across all datasets (train AUC\u2009=\u20090.912; validation AUC\u2009=\u20090.864; test AUC\u2009=\u20090.817), significantly outperforming traditional radiomics (AUC range: 0.742\u20130.837) and clinical models (AUC range: 0.826\u20130.841). Integration of DL3D, radiomics, and clinical features into a combined multimodal model further enhanced predictive accuracy, yielding AUCs of 0.927 (train), 0.867 (validation), and 0.847 (test). Notably, both junior and senior radiologists demonstrated substantially lower diagnostic accuracy (AUC range: 0.586\u20130.623) compared to all models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The standalone DL3D model significantly surpassed expert assessments, with the combined model delivering the most pronounced performance advantage over human interpretation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70874","type":"journal-article","created":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T11:45:43Z","timestamp":1771242343000},"page":"454-467","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>3D<\/scp>\n                    deep\u2010learning radiomics from\n                    <scp>MR<\/scp>\n                    \u2010\n                    <scp>T2WI<\/scp>\n                    for predicting placenta accreta spectrum disorders: A multicenter study"],"prefix":"10.1002","volume":"174","author":[{"given":"Xirong","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Medical Techniques Shaanxi University of Chinese Medicine  Xianyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8523-2772","authenticated-orcid":false,"given":"Changyi","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Radiology The Second Affiliated Hospital of Shaanxi University of Chinese Medicine  Xianyang China"},{"name":"The First School of Clinical Medicine of Lanzhou University  Lanzhou China"},{"name":"Department of Radiology The First Hospital of Lanzhou University  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunlin","family":"Guo","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine of Lanzhou University  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Affiliated Hospital  Yan'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology First People's Hospital of Shangqiu  Shangqiu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.05.067"},{"issue":"10","key":"e_1_2_10_3_1","first-page":"17","article-title":"Notice on issuing the maternal and child safety action improvement plan (2021\u20102025)","author":"National Health Commission of the People's Republic of China","year":"2021","journal-title":"Gazette of the National Health Commission of the People's Republic of 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