{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T07:19:41Z","timestamp":1789802381211,"version":"4.0.1"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp;amp; Obste"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The effect of parity on labor progression following term pre\u2010labor rupture of membranes (PROM) has been described, but detailed patterns among grand multiparous women remain unclear. Traditional labor models show accelerated labor with increasing parity, yet few studies have specifically examined PROM latency distributions or heterogeneity within high\u2010parity groups. The aim of the present study was to characterize labor progression after term PROM across parity groups, with specific focus on identifying heterogeneity and distinct distributional patterns among grand multiparous women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This was a retrospective cohort study including 11\u2009219 women with singleton, cephalic pregnancies at \u226537\u2009weeks gestation who underwent expectant management following term PROM. Women were stratified into three groups: nulliparous (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094347), multiparous parity 1\u20134 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096725), and grand multiparous parity \u22655 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009147). The primary outcome was PROM\u2010to\u2010delivery interval analyzed by mean, median, and percentile distribution. Secondary outcomes included mode of delivery and second\u2010stage duration.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean PROM\u2010to\u2010delivery interval decreased with increasing parity (nulliparous 13.4\u2009\u00b1\u20097.1\u2009h vs multiparous 10.4\u2009\u00b1\u20096.3\u2009h vs grand multiparous 10.2\u2009\u00b1\u20096.5\u2009h;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). While grand multiparous women had labor kinetics comparable to multiparous women at lower percentiles, a biphasic pattern emerged: beyond the 70th percentile, latency in grand multiparous women plateaued and resembled nulliparous progression. Grand multiparous women had the shortest second stage (14.3\u2009\u00b1\u20099.8\u2009min) and highest spontaneous vaginal delivery rate (96.6%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Beyond confirming known parity\u2010related differences in labor duration after term PROM, this study demonstrates clinically relevant heterogeneity within the grand multiparous population. A distinct subgroup shows delayed progression that is not captured by mean or median estimates. Distributional, percentile\u2010based assessment may refine counseling and support more individualized timing of intervention following term PROM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70953","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T08:55:40Z","timestamp":1773392140000},"page":"1374-1380","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Time from pre\u2010labor rupture of membrane at term to delivery in grand multiparous women"],"prefix":"10.1002","volume":"174","author":[{"given":"Shai","family":"Ram","sequence":"first","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center, Affiliated to the Gray Faculty of Medicine and Health Science Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8431-8563","authenticated-orcid":false,"given":"Michael","family":"Lavie","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center, Affiliated to the Gray Faculty of Medicine and Health Science Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Bitan","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center, Affiliated to the Gray Faculty of Medicine and Health Science Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Nadav","family":"Sabag","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center, Affiliated to the Gray Faculty of Medicine and Health Science Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dotan","family":"Madar","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center, Affiliated to the Gray Faculty of Medicine and Health Science Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"Lavie","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center, Affiliated to the Gray Faculty of Medicine and Health Science Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yariv","family":"Yogev","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center, Affiliated to the Gray Faculty of Medicine and Health Science Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roza","family":"Berkovitz Shperling","sequence":"additional","affiliation":[{"name":"Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center, Affiliated to the Gray Faculty of Medicine and Health Science Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"issue":"8","key":"e_1_2_9_2_1","first-page":"26346","article-title":"Evaluation and management of premature rupture of membranes: a review article","volume":"5","author":"Garg A","year":"2017","journal-title":"J Med Sci Clin Res"},{"issue":"1","key":"e_1_2_9_3_1","article-title":"Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37\u2009weeks or more)","volume":"1","author":"Middleton P","year":"2017","journal-title":"Cochrane Database Syst 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