{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T15:08:46Z","timestamp":1784300926061,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the impact of both pre\u2010 and post\u2010ovulation post\u2010wash total progressive motile sperm count (TPMSC) on pregnancy outcomes in intrauterine insemination (IUI) using husband's sperm (AIH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective cohort study analyzed data from infertile couples who underwent IUI treatment at the Reproductive Medicine Center of Xinxiang Central Hospital from January 2020 to June 2024. A total of 462 IUI cycles were included, all of which had consistent pre\u2010 and post\u2010ovulation post\u2010wash TPMSC values. Cycles were divided into four groups based on TPMSC: Group A (&lt;10\u2009\u00d7\u200910\n                      <jats:sup>6<\/jats:sup>\n                      ), Group B (10\u201320\u2009\u00d7\u200910\n                      <jats:sup>6<\/jats:sup>\n                      ), Group C (20\u201330\u2009\u00d7\u200910\n                      <jats:sup>6<\/jats:sup>\n                      ), and Group D (\u2265\u200930\u2009\u00d7\u200910\n                      <jats:sup>6<\/jats:sup>\n                      ). Comparisons were made regarding baseline data and pregnancy outcomes among the groups. Multivariate logistic regression was employed to assess the impact of both pre\u2010 and post\u2010ovulation post\u2010wash TPMSC on clinical pregnancy rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The clinical pregnancy rates differed significantly among TPMSC groups (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.024), with the highest rate in the 10\u201320\u2009\u00d7\u200910\n                      <jats:sup>6<\/jats:sup>\n                      group (26.13%). Multivariate logistic regression identified this range as an independent predictor of clinical pregnancy (odds ratio [OR]\u2009=\u20091.922, 95% confidence interval [CI]: 1.026\u20133.600,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.041).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Post\u2010wash TPMSC influences clinical pregnancy rates in IUI. When both pre\u2010 and post\u2010ovulation post\u2010wash TPMSC are within the range of 10\u201320\u2009\u00d7\u200910\n                      <jats:sup>6<\/jats:sup>\n                      , this may optimize clinical pregnancy outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.70982","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T10:45:50Z","timestamp":1774262750000},"page":"1081-1086","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Optimizing post\u2010wash\n                    <scp>TPMSC<\/scp>\n                    for intrauterine insemination: A key strategy to improve pregnancy outcomes"],"prefix":"10.1002","volume":"174","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6592-437X","authenticated-orcid":false,"given":"Zhiyong","family":"Li","sequence":"first","affiliation":[{"name":"Xinxiang Central Hospital  Xinxiang Henan 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Henan China"},{"name":"Department of Reproductive Medicine Xinxiang Central Hospital  Xinxiang Henan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Hai","sequence":"additional","affiliation":[{"name":"Xinxiang Central Hospital  Xinxiang Henan China"},{"name":"The Fourth Clinical College of Henan Medical University  Xinxiang Henan China"},{"name":"Department of Reproductive Medicine Xinxiang Central Hospital  Xinxiang Henan 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