{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:14:48Z","timestamp":1747149288848,"version":"3.40.5"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T00:00:00Z","timestamp":1640822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>We present a case of novel coronavirus disease\u20102019 that underwent combination therapy with nivolumab and ipilimumab for metastatic renal cell carcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 50\u2010year\u2010old man complained of anorexia and weight loss. Contrast\u2010enhanced computed tomography revealed a solid mass of 57\u2009mm in diameter with cysts in the right kidney, along with liver, lung, and multiple bone metastases. Computed tomography\u2010guided biopsy of the right kidney was performed, and a diagnosis of clear cell renal cell carcinoma was made. Three weeks after nivolumab and ipilimumab administration, the patient contracted coronavirus disease\u20102019. Anticoagulation therapy (dalteparin) was administered for 4\u2009days once infection was confirmed, after which dexamethasone was administered for 10\u2009days. The patient survived without experiencing worsened respiratory symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We administered nivolumab and ipilimumab combination therapy as treatment for metastatic renal cell carcinoma. No side effects or immune\u2010related adverse events were observed for a short time.<\/jats:p><\/jats:sec>","DOI":"10.1002\/iju5.12412","type":"journal-article","created":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T01:52:55Z","timestamp":1640915575000},"page":"126-128","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A case of novel coronavirus disease after combination therapy with nivolumab and ipilimumab for metastatic renal cell carcinoma"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5760-445X","authenticated-orcid":false,"given":"Yu","family":"Kijima","sequence":"first","affiliation":[{"name":"Department of Urology and Transplant Surgery Toda Chuo General Hospital Saitama Japan"},{"name":"Department of Urology Tokyo Women\u2019s Medical University Tokyo 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