{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T14:14:06Z","timestamp":1758809646415,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T00:00:00Z","timestamp":1648598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>We present tri\u2010modality therapy with i\u2010125 brachytherapy for high\u2010risk prostate cancer after holmium laser enucleation of the prostate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 75\u2010year\u2010old man had visited our hospital with complaints of dysuria. Holmium laser enucleation of the prostate was performed for benign prostatic hyperplasia. The resected histopathological prostate tissue showed malignancy (Gleason score: 3\u2009+\u20093\u2009=\u20096). Two years thereafter, Gleason score progressed (4\u2009+\u20095\u2009=\u20099) concomitantly with increased prostate\u2010specific antigen levels. Therefore, tri\u2010modality therapy, including brachytherapy, was applied. Combined androgen blockade therapy was conducted over a 9\u2010month period. One month after brachytherapy, external beam radiation was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Brachytherapy following transurethral prostate surgery is relatively contraindicated because of increased adverse urethral event frequency and seed placement difficulties. A tri\u2010modality therapy, including brachytherapy, was implemented without any major problems in this patient with high\u2010risk prostate cancer after holmium laser enucleation of the prostate, following which he had a favorable prognosis without recurrence for 6\u2009years.<\/jats:p><\/jats:sec>","DOI":"10.1002\/iju5.12437","type":"journal-article","created":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T08:15:33Z","timestamp":1648628133000},"page":"223-226","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Tri\u2010modality therapy with i\u2010125 brachytherapy, external beam radiation therapy, and short\u2010term hormone therapy for high\u2010risk prostate cancer after holmium laser enucleation of the prostate"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5595-7075","authenticated-orcid":false,"given":"Makoto","family":"Nakiri","sequence":"first","affiliation":[{"name":"Departments of Urology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosuke","family":"Ueda","sequence":"additional","affiliation":[{"name":"Departments of Urology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoyuki","family":"Ogasawara","sequence":"additional","affiliation":[{"name":"Departments of Urology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0395-9490","authenticated-orcid":false,"given":"Hirofumi","family":"Kurose","sequence":"additional","affiliation":[{"name":"Departments of Urology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichiro","family":"Uemura","sequence":"additional","affiliation":[{"name":"Departments of Urology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoaki","family":"Nishihara","sequence":"additional","affiliation":[{"name":"Departments of Urology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichiro","family":"Muraki","sequence":"additional","affiliation":[{"name":"Department of Radiology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikayuki","family":"Hattori","sequence":"additional","affiliation":[{"name":"Department of Radiology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etsuyo","family":"Ogo","sequence":"additional","affiliation":[{"name":"Department of Radiology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsukasa","family":"Igawa","sequence":"additional","affiliation":[{"name":"Departments of Urology Kurume University School of Medicine  Kurume Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,30]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_16_2_1","DOI":"10.1001\/jama.280.11.969"},{"doi-asserted-by":"publisher","key":"e_1_2_16_3_1","DOI":"10.1016\/S0360-3016(03)00784-3"},{"doi-asserted-by":"publisher","key":"e_1_2_16_4_1","DOI":"10.1200\/JCO.2008.20.3992"},{"doi-asserted-by":"publisher","key":"e_1_2_16_5_1","DOI":"10.1016\/j.brachy.2014.08.047"},{"doi-asserted-by":"publisher","key":"e_1_2_16_6_1","DOI":"10.1111\/j.1464-410X.2011.10827.x"},{"doi-asserted-by":"publisher","key":"e_1_2_16_7_1","DOI":"10.5114\/jcb.2017.66072"},{"doi-asserted-by":"publisher","key":"e_1_2_16_8_1","DOI":"10.1111\/j.1464-410X.2009.08661.x"},{"doi-asserted-by":"publisher","key":"e_1_2_16_9_1","DOI":"10.1016\/j.urology.2008.09.059"},{"doi-asserted-by":"publisher","key":"e_1_2_16_10_1","DOI":"10.1016\/j.urology.2008.03.019"},{"doi-asserted-by":"publisher","key":"e_1_2_16_11_1","DOI":"10.1016\/j.juro.2007.03.114"},{"doi-asserted-by":"publisher","key":"e_1_2_16_12_1","DOI":"10.1016\/j.juro.2006.07.140"},{"doi-asserted-by":"publisher","key":"e_1_2_16_13_1","DOI":"10.1097\/00000478-198812000-00001"}],"container-title":["IJU Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iju5.12437","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/iju5.12437","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iju5.12437","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T20:11:35Z","timestamp":1692821495000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/iju5.12437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,30]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1002\/iju5.12437"],"URL":"https:\/\/doi.org\/10.1002\/iju5.12437","archive":["Portico"],"relation":{},"ISSN":["2577-171X","2577-171X"],"issn-type":[{"type":"print","value":"2577-171X"},{"type":"electronic","value":"2577-171X"}],"subject":[],"published":{"date-parts":[[2022,3,30]]},"assertion":[{"value":"2021-11-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}