{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:43:24Z","timestamp":1786977804564,"version":"build-2736575974"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Granulocyte colony\u2010stimulating factor\u2010associated aortitis remains poorly understood among clinicians.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We present a case of G\u2010CSF\u2010associated aortitis in a 70\u2010year\u2010old male with stage IVb castration\u2010resistant prostate cancer (cT3bN0M1b) receiving docetaxel chemotherapy. Neutropenia (280\/\u03bcL) developed on day 8 of the first chemotherapy cycle, prompting subcutaneous administration of filgrastim, a short\u2010acting G\u2010CSF, on days 8\u201310. On day 14, the patient presented to the outpatient clinic with fever but no other significant symptoms. Computed tomography revealed filgrastim\u2010induced thoracic aortitis. Daily prednisone treatment (equivalent to 25\u2009mg prednisolone) was initiated on the following day. Although the initial episode of aortitis resolved within 5\u2009weeks, subsequent pegfilgrastim resulted in recurrence around the left subclavian artery, necessitating further steroid therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Persistent high fever following G\u2010CSF administration may indicate drug\u2010induced aortitis, highlighting the potential for aortitis recurrence with repeated G\u2010CSF use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iju5.12835","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T19:04:41Z","timestamp":1739473481000},"page":"190-193","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Granulocyte colony\u2010stimulating factor\u2010associated aortitis in a man with advanced prostate cancer"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1596-891X","authenticated-orcid":false,"given":"Ryota","family":"Ikadai","sequence":"first","affiliation":[{"name":"Department of Urology Aichi Cancer Center Hospital  Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9008-6356","authenticated-orcid":false,"given":"Goshi","family":"Kitano","sequence":"additional","affiliation":[{"name":"Department of Urology Aichi Cancer Center Hospital  Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2130-4682","authenticated-orcid":false,"given":"Manabu","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Urology Aichi Cancer Center Hospital  Nagoya Aichi 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drug\u2010induced vasculitis during administration of pegfilgrastim","volume":"58","author":"Ito Y","year":"2017","journal-title":"Rinsho Ketsueki"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-019-02662-6"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1253\/circrep.CR-20-0092"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-024-03744-w"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezx165"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1808850115"},{"key":"e_1_2_13_16_1","article-title":"The epidemiology and clinical manifestations of Takayasu arteritis: a descriptive study of case reports","volume":"13","author":"Alnabwani D","year":"2021","journal-title":"Cureus"}],"container-title":["IJU Case 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