{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:10:08Z","timestamp":1746576608571,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T00:00:00Z","timestamp":1739145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Well\u2010differentiated neuroendocrine tumors of the kidney are rare and generally less aggressive than renal cell carcinoma, although metastasis is still present at the time of diagnosis. Surgical resection remains the preferred treatment, even in cases with lymph node metastases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>We present the case of a 38\u2010year\u2010old female with a right renal WDNET and lymph node metastasis who underwent laparoscopic radical nephrectomy with lymphadenectomy. Pathological examination confirmed metastasis in 9 out of 11 lymph nodes. Immunohistochemistry results were positive for synaptophysin and chromogranin, with a Ki\u201067 index of less than 10%. No recurrence was observed after 36\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Well\u2010differentiated neuroendocrine tumors are rare, with non\u2010specific clinical and imaging characteristics, requiring immunohistochemical analysis for diagnosis. Surgical resection is the treatment of choice, and long\u2010term follow\u2010up is essential.<\/jats:p><\/jats:sec>","DOI":"10.1002\/iju5.70005","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T05:51:42Z","timestamp":1739253102000},"page":"202-205","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary renal well\u2010differentiated neuroendocrine tumors with lymph node metastasis: A case report and literature review"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9815-6131","authenticated-orcid":false,"given":"Huy\u2010Hoang","family":"Nguyen","sequence":"first","affiliation":[{"name":"Department of Urologic Surgery Viet Duc University Hospital  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoang\u2010Giang","family":"Phan","sequence":"additional","affiliation":[{"name":"Radiology Center Bach Mai Hospital  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duc\u2010Thuong","family":"Ho","sequence":"additional","affiliation":[{"name":"Pathology Department Viet Duc University Hospital  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6293-7913","authenticated-orcid":false,"given":"Van\u2010Hung","family":"Le","sequence":"additional","affiliation":[{"name":"Center of Gastroenterology \u2013 Hepatology \u2013 Urology Vinmec International Hospital  Hanoi Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,10]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_13_2_1","DOI":"10.1186\/s12885-019-6412-8"},{"doi-asserted-by":"publisher","key":"e_1_2_13_3_1","DOI":"10.1001\/jamaoncol.2017.0589"},{"doi-asserted-by":"publisher","key":"e_1_2_13_4_1","DOI":"10.1177\/03000605231198384"},{"doi-asserted-by":"publisher","key":"e_1_2_13_5_1","DOI":"10.1038\/s41379-018-0110-y"},{"key":"e_1_2_13_6_1","first-page":"189","volume-title":"WHO classification of of tumours of the urinary system and male genital organs","author":"Ulbright TM","year":"2016"},{"doi-asserted-by":"publisher","key":"e_1_2_13_7_1","DOI":"10.5858\/2006-130-1693-CTOTUT"},{"doi-asserted-by":"publisher","key":"e_1_2_13_8_1","DOI":"10.2147\/OTT.S364545"},{"doi-asserted-by":"publisher","key":"e_1_2_13_9_1","DOI":"10.1016\/j.critrevonc.2013.02.003"},{"doi-asserted-by":"publisher","key":"e_1_2_13_10_1","DOI":"10.4329\/wjr.v5.i8.328"},{"key":"e_1_2_13_11_1","first-page":"851","article-title":"Clinicopathologic features of primary renal neuroendocrine carcinoma","volume":"47","author":"Wang XH","year":"2018","journal-title":"Zhonghua Bing Li Xue Za Zhi"},{"doi-asserted-by":"publisher","key":"e_1_2_13_12_1","DOI":"10.1016\/j.juro.2006.07.129"},{"doi-asserted-by":"publisher","key":"e_1_2_13_13_1","DOI":"10.1097\/PAP.0b013e3180ca8a89"},{"doi-asserted-by":"publisher","key":"e_1_2_13_14_1","DOI":"10.1155\/2013\/579396"},{"doi-asserted-by":"publisher","key":"e_1_2_13_15_1","DOI":"10.1016\/j.clgc.2020.10.010"},{"doi-asserted-by":"publisher","key":"e_1_2_13_16_1","DOI":"10.5489\/cuaj.1091"},{"doi-asserted-by":"publisher","key":"e_1_2_13_17_1","DOI":"10.1002\/1097-0142(19931101)72:9<2660::AID-CNCR2820720923>3.0.CO;2-O"},{"doi-asserted-by":"publisher","key":"e_1_2_13_18_1","DOI":"10.1016\/j.acuro.2010.02.043"},{"doi-asserted-by":"publisher","key":"e_1_2_13_19_1","DOI":"10.1016\/j.nucmedbio.2008.05.008"}],"container-title":["IJU Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iju5.70005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T23:43:26Z","timestamp":1746575006000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/iju5.70005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,10]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/iju5.70005"],"URL":"https:\/\/doi.org\/10.1002\/iju5.70005","archive":["Portico"],"relation":{},"ISSN":["2577-171X","2577-171X"],"issn-type":[{"type":"print","value":"2577-171X"},{"type":"electronic","value":"2577-171X"}],"subject":[],"published":{"date-parts":[[2025,2,10]]},"assertion":[{"value":"2024-11-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}