{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T21:22:43Z","timestamp":1773523363787,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The frequency of granulocyte colony\u2010stimulating factor\u2010related aortitis is low. We report a case of successful corticosteroid treatment in a patient with prostate cancer who developed aortitis following pegfilgrastim administration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 68\u2010year\u2010old male with castration\u2010resistant prostate cancer initiated docetaxel therapy. During the second cycle, pegfilgrastim was administered for neutropenia prophylaxis. On Day 10, the patient developed a persistent fever and elevated inflammatory markers. Evaluation led to a diagnosis of granulocyte colony\u2010stimulating factor\u2010related aortitis, and corticosteroid therapy was started. After switching from pegfilgrastim to filgrastim, the patient completed eight treatment cycles without recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In patients who develop fever and elevated inflammatory markers following granulocyte colony\u2010stimulating factor administration, granulocyte colony\u2010stimulating factor\u2010related aortitis should be considered in the differential diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iju5.70110","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T03:45:28Z","timestamp":1761882328000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Successful Treatment of Granulocyte Colony\u2010Stimulating Factor\u2010Related Aortitis in Prostate Cancer"],"prefix":"10.1002","volume":"9","author":[{"given":"Shota","family":"Yamada","sequence":"first","affiliation":[{"name":"Department of Urology Nagasaki University Graduate School of Biomedical Sciences  Nagasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kota","family":"Amamoto","sequence":"additional","affiliation":[{"name":"Department of Urology Sasebo City General Medical Center  Nagasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhide","family":"Maekawa","sequence":"additional","affiliation":[{"name":"Department of Urology Sasebo City General Medical Center  Nagasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazusato","family":"Hara","sequence":"additional","affiliation":[{"name":"Department of Immunology and Rheumatology Nagasaki University Graduate School of Biomedical Sciences  Nagasaki 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