{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T01:55:16Z","timestamp":1774576516482,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pituitary apoplexy represents an uncommon endocrine emergency with potentially life\u2010threatening consequences. Gonadotropin\u2010releasing hormone agonist used for prostate cancer has the potential to induce pituitary apoplexy, particularly in the setting of a preexisting pituitary adenoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 76\u2010year\u2010old male with prostate cancer initially chose active surveillance; however, prostate\u2010specific antigen (PSA) elevation required hormonal therapy 5\u2009years later. A pancreatic islet tumor had been previously identified; however, its details were unavailable. He was presented to the emergency department 24\u2009h after receiving the first gonadotropin\u2010releasing hormone agonist injection. He showed severe headache, general fatigue, diplopia, and ptosis of the right eye. Brain MRI revealed a right deviated suprasellar pituitary adenoma with hemorrhagic infarction. He was conservatively treated with high\u2010dose steroids; symptoms improved within 1\u2009week.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Clinicians should be aware of the association of pituitary apoplexy with the use of gonadotropin\u2010releasing hormone agonist and should ask about the patient's past history of multiple endocrine neoplasia (MEN).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iju5.70159","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:40:43Z","timestamp":1773009643000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pituitary Apoplexy Following Gonadotropin\u2010Releasing Hormone Agonist Administration for Prostate Cancer"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2201-8044","authenticated-orcid":false,"given":"Masaaki","family":"Fujimura","sequence":"first","affiliation":[{"name":"Department of Urology Chibaken Saiseikai Narashino Hospital  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Urology Chiba University  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Urology Chiba University  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6516-2519","authenticated-orcid":false,"given":"Hiroaki","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Urology Chibaken Saiseikai Narashino Hospital  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyoshi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Urology Toho University Medical Center Sakura Hospital  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Mikami","sequence":"additional","affiliation":[{"name":"Department of Urology Chibaken Saiseikai Narashino Hospital  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2014.08.015"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2016-218514"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2010.03913.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2006.104.6.931"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13244-014-0362-0"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-021-03697-1"},{"key":"e_1_2_9_8_1","first-page":"153","article-title":"Pituitary Apoplexy Secondary to Gonadotropin\u2010Releasing Hormone Agonist for Breast Cancer","volume":"11","author":"Mastandrea K.","year":"2023","journal-title":"JCEM Case 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