{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T04:04:27Z","timestamp":1779681867903,"version":"3.53.1"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pediatric neurogenic lower urinary tract dysfunction (NLUTD) is commonly managed with anticholinergic agents and clean intermittent catheterization (CIC). However, treatment options are limited for patients who remain resistant to conventional therapy, particularly following spinal cord surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 14\u2010year\u2010old boy with myelomeningocele underwent vertebral resection and spinal cord amputation. Despite CIC and solifenacin, he continued to experience daily urinary incontinence. 1\u2009year postoperatively, his symptoms worsened and urinalysis became abnormal. Video\u2010urodynamic study showed reduced bladder compliance and progression of bladder deformity. Vibegron 50\u2009mg once daily was initiated. At 12\u2009weeks, bladder capacity increased and compliance improved. Over 24\u2009months, no urinary tract infections, incontinence episodes, or drug\u2010related adverse events occurred.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case suggests that vibegron may be an effective, well\u2010tolerated add\u2010on therapy for pediatric patients with anticholinergic\u2010resistant NLUTD after spinal cord surgery, improving bladder function and morphology while helping maintain quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iju5.70185","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T12:18:09Z","timestamp":1778761089000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vibegron for Anticholinergic\u2010Resistant Pediatric Neurogenic Lower Urinary Tract Dysfunction After Spinal Cord Amputation: A Case Report"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1681-0567","authenticated-orcid":false,"given":"Kohei","family":"Mori","sequence":"first","affiliation":[{"name":"Department of Urology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izuru","family":"Shiba","sequence":"additional","affiliation":[{"name":"Department of Urology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruko","family":"Miyazawa","sequence":"additional","affiliation":[{"name":"Department of Urology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Samejima","sequence":"additional","affiliation":[{"name":"Department of Urology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koga","family":"Horiuchi","sequence":"additional","affiliation":[{"name":"Department of Urology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirokazu","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Urology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Shiono","sequence":"additional","affiliation":[{"name":"Department of Urology Kitasato University School of Medicine  Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazumasa","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Urology Kitasato University School of Medicine  Sagamihara 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