{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T04:04:33Z","timestamp":1779681873501,"version":"3.53.1"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T00:00:00Z","timestamp":1777766400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Although secondary bladder tumors from distant metastases are rare, those originating from hepatocellular carcinoma are particularly uncommon, with only a few cases reported to date.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>An 81 year old male with hepatocellular carcinoma developed a rapidly growing 23\u2009mm\u2010sized bladder tumor during systemic therapy with atezolizumab and bevacizumab. Cystoscopy revealed a pedunculated, nonpapillary tumor on the posterior wall of the bladder, and transurethral resection was urgently performed due to bleeding. Histopathology and immunohistochemistry confirmed bladder metastasis of hepatocellular carcinoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although rare, rapidly enlarging bladder tumors in patients with hepatocellular carcinoma should be considered as possible metastatic lesions in the differential diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iju5.70189","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T05:01:57Z","timestamp":1777870917000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Metastasis of Hepatocellular Carcinoma to the Urinary Bladder: A Case Report and Literature 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