{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T08:07:22Z","timestamp":1790323642620,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The coexistence of testicular cancer and hematopoietic disorders is rare, and reports on optimal treatment strategies are limited. Here, we present a case of metastatic testicular cancer associated with myelodysplastic syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 24\u2010year\u2010old man with pancytopenia underwent right orchiectomy for a right scrotal mass. Histopathological examination revealed embryonal carcinoma. Subsequent imaging demonstrated para\u2010aortic lymph node metastasis. Pancytopenia was diagnosed as myelodysplastic syndrome. The patient received chemotherapy with dose modifications and a prolonged treatment course, followed by retroperitoneal lymph node dissection; viable tumor cells were identified in the resected specimens. After adjuvant chemotherapy, allogenic hematopoietic stem cell transplantation was performed for myelodysplastic syndrome. The patient remained free of testicular cancer recurrence for 2\u2009years post\u2010surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case suggests that durable disease control may be achievable in metastatic testicular cancer associated with myelodysplastic syndrome through carefully managed chemotherapy and surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iju5.70233","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T07:24:37Z","timestamp":1786951477000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Metastatic Testicular Cancer Complicated by Myelodysplastic Syndrome"],"prefix":"10.1002","volume":"9","author":[{"given":"Nobuhiko","family":"Shimizu","sequence":"first","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuga","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sosuke","family":"Niwa","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8916-0806","authenticated-orcid":false,"given":"Takahiro","family":"Yanase","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0584-3712","authenticated-orcid":false,"given":"Rei","family":"Unno","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2581-4882","authenticated-orcid":false,"given":"Shoichiro","family":"Iwatsuki","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiki","family":"Etani","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2080-3794","authenticated-orcid":false,"given":"Atsushi","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Yasui","sequence":"additional","affiliation":[{"name":"Department of Nephro\u2010urology, Graduate School of Medical Sciences Nagoya City University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(25)00455\u20106"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjhh.2014.07.005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000513510"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/jcrt.JCRT_18_18"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3919\/ringe1963.54.1558"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.11641\/pde.59.2_68"},{"key":"e_1_2_11_8_1","first-page":"704","article-title":"Perioperative Management of a Lung Cancer Patient Complicated by Myelodysplastic Syndrome","volume":"16","author":"Tamura K.","year":"2002","journal-title":"Journal of the Japanese Association for Chest Surgery"},{"key":"e_1_2_11_9_1","unstructured":"National Comprehensive Cancer Network \u201cNCCN Guidelines Version 1.2026 Testicular Cancer. National Comprehensive Cancer Network \u201d 2026 https:\/\/www.nccn.org\/guidelines\/guidelines\u2010detail?category=1&id=1468."},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102012\u201003\u2010420489"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2016.00507"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(19900901)66:5<857::aid\u2010cncr2820660508>3.0.co;2\u2010g"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000282728"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyl053"}],"container-title":["IJU Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iju5.70233","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/iju5.70233","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iju5.70233","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:43:08Z","timestamp":1790322188000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/iju5.70233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,17]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/iju5.70233"],"URL":"https:\/\/doi.org\/10.1002\/iju5.70233","archive":["Portico"],"relation":{},"ISSN":["2577-171X","2577-171X"],"issn-type":[{"value":"2577-171X","type":"print"},{"value":"2577-171X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,17]]},"assertion":[{"value":"2026-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70233"}}