{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T08:06:56Z","timestamp":1790323616100,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T00:00:00Z","timestamp":1786838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T00:00:00Z","timestamp":1786838400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IJU Case Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Plasmacytoid urothelial carcinoma (PUC) is a rare, aggressive subtype of bladder cancer characterized by diffuse infiltrative growth and a propensity for peritoneal and retroperitoneal dissemination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A patient with muscle\u2010invasive bladder cancer (cT3N1M0) was diagnosed with conventional high\u2010grade urothelial carcinoma without subtype histology on transurethral resection. After neoadjuvant gemcitabine\u2013cisplatin chemotherapy, robot\u2010assisted radical cystectomy with intracorporeal neobladder reconstruction was performed. Final pathological examination revealed PUC (pT4aN2). Within weeks after surgery, the patient developed sequential retroperitoneal fluid accumulation, bilateral hydronephrosis, duodenal obstruction, and biliary obstruction, suggesting rapid diffuse retroperitoneal progression. Enfortumab vedotin plus pembrolizumab was initiated; however, the disease progressed aggressively, and the patient died on postoperative day 80.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PUC may evade detection on initial TUR and can progress rapidly through diffuse retroperitoneal dissemination even after radical cystectomy. Early postoperative, unexplained multiorgan obstructive findings should raise suspicion of occult progression and prompt timely initiation of systemic therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iju5.70249","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T05:37:22Z","timestamp":1786945042000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rapidly Progressive Retroperitoneal Dissemination of Plasmacytoid Urothelial Carcinoma Presenting With Multiorgan Obstruction After Radical Cystectomy: A Case Report"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4908-9444","authenticated-orcid":false,"given":"Mahito","family":"Atsuta","sequence":"first","affiliation":[{"name":"Department of Urology The Jikei University Kashiwa Hospital  Chiba Japan"},{"name":"Department of Urology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5743-7373","authenticated-orcid":false,"given":"Naoki","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Urology The Jikei University Kashiwa Hospital  Chiba Japan"},{"name":"Department of Urology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirokazu","family":"Kagawa","sequence":"additional","affiliation":[{"name":"Department of Urology The Jikei University Kashiwa Hospital  Chiba Japan"},{"name":"Department of Urology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9599-3507","authenticated-orcid":false,"given":"Naoya","family":"Tomomasa","sequence":"additional","affiliation":[{"name":"Department of Urology The Jikei University Kashiwa Hospital  Chiba Japan"},{"name":"Department of Urology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Urology The Jikei University Kashiwa Hospital  Chiba Japan"},{"name":"Department of Urology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0633-9959","authenticated-orcid":false,"given":"Kazuhiro","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Urology The Jikei University Kashiwa Hospital  Chiba Japan"},{"name":"Department of Urology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5428-852X","authenticated-orcid":false,"given":"Kosuke","family":"Iwatani","sequence":"additional","affiliation":[{"name":"Department of Urology The Jikei University Kashiwa Hospital  Chiba Japan"},{"name":"Department of Urology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4852-7704","authenticated-orcid":false,"given":"Shun","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Pathology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5673-1553","authenticated-orcid":false,"given":"Takahiro","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Urology The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4638-8640","authenticated-orcid":false,"given":"Jun","family":"Miki","sequence":"additional","affiliation":[{"name":"Department of Urology The Jikei University Kashiwa Hospital  Chiba 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