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Prenatal mental health and subjective birth experience are both predictors of postpartum bonding. The purpose of this study was to investigate how prenatal depression, anxiety, and stress were related to bonding and whether these relationships were mediated by birth experience. This prospective cohort study included a diverse sample of 108 pregnant women (38% non\u2010Hispanic White, 37% Black, 25% another race\/ethnicity) in the Northeastern United States, approximately half of whom had a mental health condition. Participants completed assessments during pregnancy and 5\u20137 weeks postpartum, including self\u2010report measures of depression, generalized anxiety, perceived stress, birth experience, and postpartum bonding. Mediation analyses were conducted to explore the relationships between prenatal mental health symptoms, birth experience, and postpartum bonding. Higher levels of prenatal stress and depression symptoms predicted poorer postpartum bonding. These relationships were partially mediated by subjective birth experience. Generalized anxiety symptoms during pregnancy were not related to bonding. Results highlight the key role of the birth experience for postpartum bonding. Mental health symptoms early in pregnancy may impact subjective birth experience and postpartum bonding, suggesting that early interventions have the potential to improve maternal well\u2010being and mother\u2013infant bonding.<\/jats:p>","DOI":"10.1002\/imhj.70074","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T08:02:13Z","timestamp":1768982533000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Birth experience partially mediates link between prenatal mental health symptoms and postpartum bonding"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6636-1034","authenticated-orcid":false,"given":"Emily D.","family":"Barnes","sequence":"first","affiliation":[{"name":"Department of Counseling Psychology &amp; Applied Human Development Boston University  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah L.","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Boston University Chobanian &amp; Avedisian School of Medicine  Boston Massachusetts USA"},{"name":"Department of Epidemiology Boston University School of Public Health  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Elansary","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Boston University Chobanian &amp; Avedisian School of Medicine Boston Medical Center  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawne","family":"Vogt","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Boston University Chobanian &amp; Avedisian School of Medicine  Boston Massachusetts USA"},{"name":"National Center for PTSD Women's Health Sciences Division at VA Boston Healthcare System  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varsha","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Department of Mathematics &amp; Statistics Boston University  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yael I.","family":"Nillni","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Boston University Chobanian &amp; Avedisian School of Medicine  Boston Massachusetts USA"},{"name":"National Center for PTSD Women's Health Sciences Division at VA Boston Healthcare System  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995\u2010021\u201003225\u20100"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000005200"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/0887044042000272912"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2023.102761"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737\u2010018\u20100921\u20103"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18168517"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02105408"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737\u2010006\u20100132\u20101"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.2307\/2136404"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2021.01.023"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.infbeh.2023.101871"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737\u2010014\u20100445\u20104"},{"issue":"4","key":"e_1_2_8_14_1","first-page":"128","article-title":"Risk factors and assessment tools for mother\u2010infant bonding: A scoping review to assist future research","volume":"15","author":"Edwards H.","year":"2017","journal-title":"Evidence Based Midwifery"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2022.815822"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/DBP.0000000000000998"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737-017-0785-y"},{"key":"e_1_2_8_18_1","volume-title":"Structured clinical interview for DSM\u20105 disorders, clinician version (SCID\u20105\u2010CV)","author":"First M. 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