{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T02:51:52Z","timestamp":1789613512710,"version":"build-2803163510"},"reference-count":108,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T00:00:00Z","timestamp":1574726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["iubmb.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IUBMB Life"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Viral replication and related protein expression inside the host cells, and host antiviral immune responses can lead to the occurrence of diverse diseases. With the outbreak of viral infection, a large number of newly diagnosed and died patients infected with various viruses are still reported every year. Viral infection has already been one of the major global public health issues and lead to huge economic and social burdens. Studying of viral pathogenesis is a very important way to find methods for prevention, diagnosis, and cure of viral infection; more evidence has confirmed that major vault protein (MVP) is closely associated with viral infection and pathogenesis, and this review is intended to provide a broad relationship between viruses and MVP to stimulate the interest of related researchers.<\/jats:p>","DOI":"10.1002\/iub.2200","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T16:20:54Z","timestamp":1574785254000},"page":"624-631","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Major vault protein plays important roles in viral infection"],"prefix":"10.1002","volume":"72","author":[{"given":"Wei","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory, Puai Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Liyuan Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6801-0705","authenticated-orcid":false,"given":"Pengyun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Liyuan Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5971-2622","authenticated-orcid":false,"given":"Fubing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Zhongnan Hospital of Wuhan University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1676-3235","authenticated-orcid":false,"given":"Qingfeng","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Liyuan Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1593"},{"key":"e_1_2_11_3_1","first-page":"141","article-title":"Significance of HBV DNA by PCR over serological markers of HBV in acute and chronic patients. Indian","volume":"19","author":"Rodrigues C","year":"2001","journal-title":"J Med Microbi"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.6.2825-2828.2004"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-8-508"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411100"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00004-08"},{"key":"e_1_2_11_8_1","first-page":"S39","article-title":"The influenza viruses","volume":"185","author":"Hampson AW","year":"2006","journal-title":"Medizinhist J"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.9.4666-4670.2002"},{"key":"e_1_2_11_10_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/3819719","article-title":"Physiological and pathological function of serine\/arginine\u2010rich splicing factor 4 and related diseases","volume":"3819719","author":"Tan W","year":"2018","journal-title":"Biomed Res Int"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000085"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.11.035"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.103.3.699"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-003-3030-y"},{"key":"e_1_2_11_15_1","first-page":"4214","article-title":"The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: Evidence that chromosome breakage plays a key role in MRP or LRP gene amplification","volume":"55","author":"Slovak ML","year":"1995","journal-title":"Cancer Res"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.110.4.895"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2004.09.021"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0695-578"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.146.5.917"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.11.006"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.46.32712"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.15.8971"},{"key":"e_1_2_11_23_1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1242\/jcs.106.1.23","article-title":"Evidence that vault ribonucleoprotein particles localize to the nuclear pore complex","volume":"106","author":"Chugani DC","year":"1993","journal-title":"J Cell Sci"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1997.8676"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.4077\/CJP.2016.BAF426"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2013.1428"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2013.05.067"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-0423"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M207608200"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2006.05112.x"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.02773"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-0124"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600803"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2008.96"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.8.1.18218"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1142311"},{"key":"e_1_2_11_37_1","first-page":"213","article-title":"Evaluation of MDR1, LRP, MRP, and topoisomerase IIalpha gene mRNA transcripts before and after interferon\u2010alpha, and correlation with the mRNA expression level of the telomerase subunits hTERTand TEP1 in five unselected human melanoma cell lines","volume":"23","author":"Miracco C","year":"2003","journal-title":"Int J Oncol"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2008.00737.x"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.02.015"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1132998"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20080091"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature03464"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.19.1.623"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2007.06.002"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxh186"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2004.04.011"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2008.00731.x"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09907"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1501481"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri910"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.278.5339.860"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.12.116"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.08.013"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)61412-X"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0801644"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04904-7"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.38.5.258"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11901-010-0055-1"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta4330"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M414139200"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cr.7290309"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2079"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2137"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1606"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/383443a0"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.25642"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26064"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22751"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2009.04.031"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2006.03261.x"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2011.01.034"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-2463"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.26.1.261-276.2006"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.21.10193"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2005.00332.x"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.01589"},{"key":"e_1_2_11_77_1","first-page":"129","article-title":"The role of Jun, Fos and the AP\u20101 complex in cell\u2010proliferation and transformation","volume":"1072","author":"Angel P","year":"1991","journal-title":"BBA\u2010Rev Cancer"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(88)90076-1"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrrev.2009.01.001"},{"key":"e_1_2_11_80_1","first-page":"1308","article-title":"Effects of IL\u201010 and IL\u20104 on LPS\u2010induced transcription factors (AP\u20101, NF\u2010IL6 and NF\u2010kappa B) which are involved in IL\u20106 regulation","volume":"10","author":"Dokter WH","year":"1996","journal-title":"Leukemia"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.71.7.5692-5695.1997"},{"key":"e_1_2_11_82_1","first-page":"213","article-title":"CCAAT\/enhancer binding proteins are critical components of the transcriptional regulation of hematopoiesis","volume":"1","author":"Yamanaka R","year":"1998","journal-title":"Int J Mol Med"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.8.5378"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.6.3368"},{"key":"e_1_2_11_85_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0020053"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(91)90760-9"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.384"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i31.7030"},{"key":"e_1_2_11_89_1","first-page":"4886","article-title":"Public health risks associated with hepatitis E virus (HEV) as a food\u2010borne pathogen","volume":"15","author":"Ricci A","year":"2017","journal-title":"EFSA"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12929"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61034-5"},{"key":"e_1_2_11_92_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0708687"},{"key":"e_1_2_11_93_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.22014"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq282"},{"key":"e_1_2_11_95_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215246"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005223"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.066142-0"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.3390\/v10060301"},{"key":"e_1_2_11_99_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-005-1086-8"},{"key":"e_1_2_11_100_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.60.041807.123549"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/387183a0"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1600343"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2008.09.005"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2009.03.003"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0809556"},{"key":"e_1_2_11_106_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-011-0061-2"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-2980-4_26"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.06168-11"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29800"}],"container-title":["IUBMB Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iub.2200","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/iub.2200","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iub.2200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T09:43:19Z","timestamp":1694079799000},"score":1,"resource":{"primary":{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/10.1002\/iub.2200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,26]]},"references-count":108,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1002\/iub.2200"],"URL":"https:\/\/doi.org\/10.1002\/iub.2200","archive":["Portico"],"relation":{},"ISSN":["1521-6543","1521-6551"],"issn-type":[{"value":"1521-6543","type":"print"},{"value":"1521-6551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,26]]},"assertion":[{"value":"2019-09-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}