{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T10:21:41Z","timestamp":1771064501226,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T00:00:00Z","timestamp":1630195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["iubmb.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IUBMB Life"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The 1\u2010year mortality and health consequences of COVID\u201019 in cancer patients are relatively underexplored. In this multicenter cohort study, 166 COVID\u201019 patients with cancer were compared with 498 non\u2010cancer COVID\u201019 patients and 498 non\u2010COVID cancer patients. The 1\u2010year all\u2010cause mortality and hospital mortality rates in Cancer COVID\u201019 Cohort (30% and 20%) were significantly higher than those in COVID\u201019 Cohort (9% and 8%, both <jats:italic>P<\/jats:italic>\u00a0&lt;\u2009.001) and Cancer Cohort (16% and 2%, both <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001). The 12\u2010month all\u2010cause post\u2010discharge mortality rate in survival discharged Cancer COVID\u201019 Cohort (8%) was higher than that in COVID\u201019 Cohort (0.4%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u2009.001) but similar to that in Cancer Cohort (15%, <jats:italic>P<\/jats:italic>\u00a0=\u2009.084). The incidence of sequelae in Cancer COVID\u201019 Cohort (23%, 26\/114) is similar to that in COVID\u201019 Cohort (30%, 130\/432, <jats:italic>P<\/jats:italic>\u00a0=\u2009.13). The 1\u2010year all\u2010cause mortality was high among patients with hematologic malignancies (59%), followed by those who have nasopharyngeal, brain, and skin tumors (45%), digestive system neoplasm (43%), and lung cancers (32%). The rate was moderate among patients with genitourinary (14%), female genital (13%), breast (11%), and thyroid tumors (0). COVID\u201019 patients with cancer showed a high rate of in\u2010hospital mortality and 1\u2010year all\u2010cause mortality, but the 12\u2010month all\u2010cause post\u2010discharge mortality rate in survival discharged cancer COVID\u201019 patients was similar to that in Cancer Cohort. Comparing to COVID\u201019 Cohort, risk stratification showed that hematologic, nasopharyngeal, brain, digestive system, and lung tumors were high risk (44% vs 9%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001), while genitourinary, female genital, breast, and thyroid tumors had moderate risk (10% vs 9%, <jats:italic>P<\/jats:italic>\u00a0=\u2009.85) in COVID\u201019 Cancer Cohort. Different tumor subtypes had different effects on COVID\u201019. But if cancer patients with COVID\u201019 manage to survive their COVID\u201019 infections, then long\u2010term mortality appears to be similar to the cancer patients without COVID\u201019, and their long\u2010term clinical sequelae were similar to the COVID\u201019 patients without cancer.<\/jats:p>","DOI":"10.1002\/iub.2536","type":"journal-article","created":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T04:08:28Z","timestamp":1627445308000},"page":"1244-1256","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["<scp>One\u2010year<\/scp> mortality and consequences of <scp>COVID<\/scp>\u201019 in cancer patients: A cohort study"],"prefix":"10.1002","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6009-3427","authenticated-orcid":false,"given":"Chen","family":"Chai","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei 430022 P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3490-2873","authenticated-orcid":false,"given":"Xiaojun","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Pathology NYU Langone Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5735-6660","authenticated-orcid":false,"given":"Meixia","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Statistics School of Public Health, Tongji Medical College, Huazhong University of Science and Technology  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5009-8013","authenticated-orcid":false,"given":"Shoupeng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei 430022 P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3910-1402","authenticated-orcid":false,"given":"Kui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Affiliated Dongfeng Hospital, Hubei University of Medicine  Shiyan Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2499-3604","authenticated-orcid":false,"given":"Hongxiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Hematology The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5659-0810","authenticated-orcid":false,"given":"Wendan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei 430022 P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoming","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Cheng","sequence":"additional","affiliation":[{"name":"Computer Center Union Hospital, Tongji Medical College, Huazhong University of Science and Technology  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxiong","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei 430022 P.R. 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei 430022 P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3750-2974","authenticated-orcid":false,"given":"Lei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei 430022 P.R. 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