{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T18:54:29Z","timestamp":1784141669973,"version":"3.55.0"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,12,14]],"date-time":"2012-12-14T00:00:00Z","timestamp":1355443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Little is known about the effects of isometric exercise on temporal summation of heat pain. Thus, the purposes of study 1 and study 2 were to examine the influence of exhaustive and non\u2010exhaustive isometric exercise on temporal summation of heat pain in men and women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010four men and 44 women (mean age\u2009=\u200920 years) completed an informed consent document and a packet of questionnaires. Ten heat pulses were applied to the thenar eminence of the dominant hand using a standardized temporal summation protocol. Participants rated the intensity of the heat pulses using a 0\u2013100 pain rating scale before and following isometric exercise consisting of squeezing a hand dynamometer at 40% of maximal voluntary contraction (<jats:styled-content style=\"fixed-case\">MVC<\/jats:styled-content>) to exhaustion (exhaustive exercise, study 1) and at 25% <jats:styled-content style=\"fixed-case\">MVC<\/jats:styled-content> for 3\u2009min (non\u2010exhaustive exercise, study 2). Muscle pain and perceived exertion were rated every 30\u2009s during exercise using validated rating scales. The data were analysed with repeated measures analysis of variance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results indicated there were no sex differences (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05) in time to exhaustion (study 1), muscle pain or perceived exertion (studies 1 and 2). There was a significant reduction (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) in temporal summation ratings following isometric exercise for men and women in both study 1 and study 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>It is concluded that exhaustive and non\u2010exhaustive isometric exercise significantly reduced temporal summation of heat pain in men and women.<\/jats:p><\/jats:sec>","DOI":"10.1002\/j.1532-2149.2012.00264.x","type":"journal-article","created":{"date-parts":[[2012,12,14]],"date-time":"2012-12-14T12:30:05Z","timestamp":1355488205000},"page":"1005-1011","source":"Crossref","is-referenced-by-count":42,"title":["Temporal summation of heat pain modulated by isometric exercise"],"prefix":"10.1002","volume":"17","author":[{"given":"K.F.","family":"Koltyn","sequence":"first","affiliation":[{"name":"Department of Kinesiology University of Wisconsin, Madison  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