{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T23:21:35Z","timestamp":1793402495797,"version":"4.5.0"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T00:00:00Z","timestamp":1363219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Identification of prognostic factors for surgery in patients with sciatica is important to be able to predict surgery in an early stage. Identification of prognostic factors predicting persistent pain, disability and recovery are important for better understanding of the clinical course, to inform patient and physician and support decision making. Consequently, we aimed to systematically review prognostic factors predicting outcome in non\u2010surgically treated patients with sciatica. A search of\n                    <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\n                    edline,\n                    <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>\n                    mbase,\n                    <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>\n                    eb of\n                    <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                    cience and\n                    <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                    inahl, up to\n                    <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\n                    arch 2012 was performed for prospective cohort studies on prognostic factors for non\u2010surgically treated sciatica. Two reviewers independently selected studies for inclusion and assessed the risk of bias. Outcomes were pain, disability, recovery and surgery. A best evidence synthesis was carried out in order to assess and summarize the data. The initial search yielded 4392 articles of which 23 articles reporting on 14 original cohorts met the inclusion criteria. High clinical, methodological and statistical heterogeneity among studies was found. Reported evidence regarding prognostic factors predicting the outcome in sciatica is limited. The majority of factors that have been evaluated, e.g., age, body mass index, smoking and sensory disturbance, showed no association with outcome. The only positive association with strong evidence was found for leg pain intensity at baseline as prognostic factor for subsequent surgery.\n                  <\/jats:p>","DOI":"10.1002\/j.1532-2149.2013.00301.x","type":"journal-article","created":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T19:02:42Z","timestamp":1363287762000},"page":"1126-1137","source":"Crossref","is-referenced-by-count":47,"title":["Systematic review of prognostic factors predicting outcome in non\u2010surgically treated patients with sciatica"],"prefix":"10.1002","volume":"17","author":[{"given":"A.J.H.","family":"Verwoerd","sequence":"first","affiliation":[{"name":"Department of General Practice Erasmus MC University Medical Center Rotterdam  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.A.J.","family":"Luijsterburg","sequence":"additional","affiliation":[{"name":"Department of General Practice Erasmus MC University Medical Center Rotterdam  The 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