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Topical application is an effective, safer alternative. Topical formulations may be extemporaneously prepared or purchased as a pre\u2010mixed hydroalcoholic solution. Adverse effects associated with topical preparations are few and mostly minor. Topical clindamycin is also used in the treatment of erythrasma, rosacea, periorificial facial dermatitis, and folliculitis.<\/jats:p>","DOI":"10.1002\/j.1875-9114.1981.tb02541.x","type":"journal-article","created":{"date-parts":[[2015,12,16]],"date-time":"2015-12-16T20:20:02Z","timestamp":1450297202000},"page":"201-205","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Topically Administered Clindamycin in the Treatment of Acne Vulgaris and Other Dermatologic Disorders"],"prefix":"10.1002","volume":"1","author":[{"given":"Theodore","family":"Rosen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Waisman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,24]]},"reference":[{"key":"e_1_2_1_1_2_2","first-page":"635","article-title":"Tetracycline, chloramphenicol, erythromycin and clindamycin","volume":"52","author":"Wilson WR.","year":"1977","journal-title":"Mayo Clin Proc"},{"key":"e_1_2_1_1_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1971.00310220131022"},{"key":"e_1_2_1_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1972.tb05095.x"},{"key":"e_1_2_1_1_5_2","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1001\/archderm.1975.01630200057005","article-title":"Clindamycin vs placebo as adjunctive therapy in moderately severe acne","volume":"111","author":"Christian GL","year":"1975","journal-title":"Arch Dermatol"},{"key":"e_1_2_1_1_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1976.01630250025007"},{"key":"e_1_2_1_1_7_2","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1001\/archderm.1976.01630310036007","article-title":"Acne vulgaris: Double\u2010blind trial comparing tetracycline and clindamycin","volume":"112","author":"Poulos ET","year":"1976","journal-title":"Arch Dermatol"},{"key":"e_1_2_1_1_8_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-81-4-429"},{"key":"e_1_2_1_1_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1976.01630270053013"},{"key":"e_1_2_1_1_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1976.03270230020020"},{"key":"e_1_2_1_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1973.03220120045012"},{"key":"e_1_2_1_1_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/135.Supplement.S95"},{"key":"e_1_2_1_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)93001-5"},{"key":"e_1_2_1_1_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197803092981003"},{"key":"e_1_2_1_1_15_2","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/0016-5085(78)90457-2","article-title":"Role of Clostridum difficile in antibiotic\u2010associated pseudomembranous colitis","volume":"75","author":"Bartlett JG","year":"1978","journal-title":"Gastroenterology"},{"key":"e_1_2_1_1_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/135.Supplement.S99"},{"key":"e_1_2_1_1_17_2","first-page":"140","article-title":"Infectious disease 1979: Antimicrobial agent\u2010induced colitis","author":"George WL","year":"1979","journal-title":"J Infect Dis"},{"key":"e_1_2_1_1_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1976.tb04389.x"},{"key":"e_1_2_1_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)91741-5"},{"key":"e_1_2_1_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(80)90851-3"},{"key":"e_1_2_1_1_21_2","first-page":"67","article-title":"Treatment of antibiotic\u2010associated pseudomembranous colitis with cholestyramine resin","volume":"143","author":"Kreutzer EW","year":"1978","journal-title":"Johns Hopkins Med J"},{"key":"e_1_2_1_1_22_2","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1001\/archderm.1979.04010040064019","article-title":"Topical antibiotics for acne vulgaris","volume":"115","author":"Stoughton RB.","year":"1979","journal-title":"Arch Dermatol"},{"key":"e_1_2_1_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(80)80253-2"},{"key":"e_1_2_1_1_24_2","first-page":"551","article-title":"Topical clindamycin in the control of acne vulgaris","volume":"17","author":"Stoughton RB","year":"1976","journal-title":"Cutis"},{"key":"e_1_2_1_1_25_2","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1001\/archderm.1976.01630260010003","article-title":"Topically applied antibiotics in acne vulgaris. 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