{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T16:40:38Z","timestamp":1773074438394,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["accpjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Am Coll Clin Pharm"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Substance use disorders (SUD) affect 17% of the United States population, and over 25% of U.S. hospitalizations are related to drug and alcohol use. Despite strong evidence and guideline recommendations, medications for SUD remain underutilized due to social stigma and institutional, legislative, and financial barriers. To address underutilization in one academic hospital, pharmacy\u2010led processes were developed for hospital\u2010administered intramuscular naltrexone (IM\u2010NTX) and hospital\u2010dispensed methadone at discharge. Workflows relied on pharmacy leadership and clinical pharmacist champions. Key steps included provider ordering, pharmacist verification, inpatient preparation, administration, chain of custody, and patient education. During the data collection period from December 2022 through March 2025, 323 orders were placed for IM\u2010NTX and verified 304 times for 248 unique patients, primarily for alcohol use disorder. Of the verified orders, 267 (88%) doses were prepared and 225 (74%) administered. Between April 2023 and May 2025, hospital\u2010dispensed methadone was ordered 231 times for 139 unique patients during 175 hospital encounters. Patients received an average 1.7\u2009days' supply per encounter, with a mean daily dose of 77\u2009mg (range 10\u2013310\u2009mg). Most dispenses (64%) occurred on Fridays and Saturdays to support weekend discharges when opioid treatment programs are typically closed in Colorado. It is estimated that this process saved 310 inpatient days over 26\u2009months.<\/jats:p>","DOI":"10.1002\/jac5.70186","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T03:20:38Z","timestamp":1771471238000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bridging the Gap: Empowering Pharmacists in Inpatient Injectable Naltrexone and Hospital\u2010Dispensed Methadone Process Development"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0863-5155","authenticated-orcid":false,"given":"Yevgeniya","family":"Scherbak","sequence":"first","affiliation":[{"name":"Department of Inpatient Pharmacy UCHealth, University of Colorado Hospital  Aurora Colorado 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of Colorado Hospital  Aurora Colorado USA"},{"name":"UCHealth Center for Dependency Addiction and Rehabilitation  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0584-7783","authenticated-orcid":false,"given":"Susan","family":"Calcaterra","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Hospital Medicine University of Colorado  Aurora Colorado USA"},{"name":"Department of Medicine, Division of General Internal Medicine University of Colorado  Aurora Colorado USA"},{"name":"Adult and Child Center for Health Outcomes Research and Delivery Service University of Colorado  Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,18]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Substance Abuse and Mental Health Services Administration \u201cHighlights for the 2023 National Survey on Drug Use and Health 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