{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T02:59:12Z","timestamp":1785380352182,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["accpjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Am Coll Clin Pharm"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>National data on clinical pharmacy implementation can inform health policy, resource allocation, workforce planning, and academic development. In Chile, such data are limited, particularly for therapeutic drug monitoring (TDM). The objective of this study was to characterize the clinical pharmacy workforce in Chilean hospitals and describe the implementation of core clinical activities, with an emphasis on TDM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A national cross\u2010sectional survey was conducted among pharmacists performing clinical functions in Chilean hospitals, using the 2024 registry of the Clinical Pharmacy Division of the Chilean Society of Intensive Care Medicine as the sampling frame. Descriptive analyses were performed; workforce capacity was expressed as full\u2010time equivalents (FTEs) and regional density per 10\u2009000 inhabitants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 220 invited pharmacists, 181 responded (82.3%), representing 83 institutions across 15 of 16 administrative regions. Median age was 35\u2009years (interquartile range [IQR] 31\u201339); 28.2% were registered Clinical Pharmacy Specialists, and 77.1% worked in public hospitals. The highest density was in the Metropolitan Region (0.12 FTE\/10000 inhabitants), followed by Tarapac\u00e1 and Antofagasta (0.09 each). Deployment was most frequent in Infectious Diseases (36.5%) and intensive care units (34.8%). Pharmacotherapy follow\u2010up and medication therapy review were each reported by 94.5%, adverse drug reaction reporting by 87.3%, and involvement in TDM by 85.1%. Teaching and research were reported by 44.8% and 30.4%, respectively, but 95.5% reported no formally protected time. TDM was available in 81.9% of centers, most commonly for vancomycin (80.7%), valproic acid (63.9%), amikacin (60.2%), and phenytoin (57.8%); pharmacokinetic software to support dose individualization was used in 61.4% of centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Clinical pharmacy services in Chile are broadly integrated into hospital care\u2014particularly in infectious diseases, critical care, and TDM\u2014while gaps persist in formal credentialing, regional workforce distribution, and institutional structures supporting academic activities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jac5.70224","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T11:45:53Z","timestamp":1778759153000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Workforce, Deployment, and Characteristics of Clinical Pharmacy in Chilean Hospitals: A Nationwide Cross\u2010Sectional Survey"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8667-8159","authenticated-orcid":false,"given":"Daniel","family":"Mu\u00f1oz","sequence":"first","affiliation":[{"name":"Escuela de Qu\u00edmica y Farmacia, Facultad de Ciencias Universidad San Sebasti\u00e1n  Valdivia Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Quezada","sequence":"additional","affiliation":[{"name":"Complejo Asistencial V\u00edctor R\u00edos Ruiz  Los \u00c1ngeles Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scarlet","family":"Tachories","sequence":"additional","affiliation":[{"name":"Hospital Carlos Van Buren  Valpara\u00edso Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Hospital Dr. Gustavo Fricke  Vi\u00f1a del Mar Chile"},{"name":"Facultad de Medicina Universidad Andr\u00e9s Bello  Sede Vi\u00f1a del Mar Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Dreyse","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Alemana de Santiago  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9rica","family":"Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Hospital Urgencia Asistencia P\u00fablica  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6457-5589","authenticated-orcid":false,"given":"Guido","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Instituto de Farmacia, Facultad de Ciencias Universidad Austral de Chile  Valdivia Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1592\/phco.28.6.816"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.9.955"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096\u2010015\u20100137\u20109"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096\u2010014\u20100008\u20109"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40545\u2010022\u201000431\u20101"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0311707"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.13195"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jac5.1854"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.4067\/s0034\u201098872023000100105"},{"key":"e_1_2_11_11_1","volume-title":"Decreto 17. 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