{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T15:38:18Z","timestamp":1793893098551,"version":"4.8.0"},"reference-count":79,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008460","name":"National Center for Complementary and Integrative Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008460","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Adolescence"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Adolescents are experiencing high rates of depressive symptoms, with negative consequences to their long\u2010term health. Group\u2010based, mindful self\u2010compassion programs show promise in mitigating the development of more significant depression in at\u2010risk adolescents. However, the lack of well\u2010designed, active control conditions has limited the ability to examine the efficacy of such interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010nine adolescents (<jats:italic>M<\/jats:italic><jats:sub>age<\/jats:sub>\u2009=\u200915.81, 70% female) with subsyndromal depressive symptoms from the Southeastern US were randomized to group\u2010based Mindful Self\u2010Compassion for Teens (<jats:italic>N<\/jats:italic>\u2009=\u200930) or a newly developed active control Healthy Lifestyles group (<jats:italic>N<\/jats:italic>\u2009=\u200929) during 2018 and 2019. Participants attended 8 weekly \u201cmain\u201d sessions followed by 6 monthly continuation sessions. The feasibility and acceptability of participation in both groups were measured using attrition, attendance, credibility, and satisfaction data. Depression scores were collected weekly, and self\u2010compassion scores were collected five times across 36 weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both groups were equally feasible and acceptable during the 8\u2010week program period; however, monthly continuation sessions were poorly attended in both groups. The risk of developing clinically significant depression was 2.6 times higher in the control group compared with the self\u2010compassion group (<jats:italic>p<\/jats:italic>\u2009=\u2009.037) across 36 weeks. Depression significantly decreased in the self\u2010compassion group, while it significantly increased in the control group. Both groups increased significantly in reports of self\u2010compassion. These findings are on par with results noting the efficacy of cognitive\u2010based interventions for high\u2010risk adolescents; follow\u2010up studies with larger sample sizes should be conducted to confirm these findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Initial examination suggests Mindful Self\u2010Compassion for Teens programming is feasible, acceptable, and efficacious in preventing the development of clinically significant depression in adolescents with subsyndromal depression. Future studies may benefit from refinements to the self\u2010compassion measurement and\/or the attention control condition; moreover, larger sample sizes are needed to confirm results.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jad.12277","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T00:52:05Z","timestamp":1701132725000},"page":"322-336","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Feasibility, acceptability, and depression outcomes of a randomized controlled trial of Mindful Self\u2010Compassion for Teens (MSC\u2010T) for adolescents with subsyndromal depression"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7535-6405","authenticated-orcid":false,"given":"Karen","family":"Bluth","sequence":"first","affiliation":[{"name":"Department of Psychiatry, University of North Carolina School of Medicine, Frank Porter Graham Child Development Institute University of North Carolina at Chapel Hill Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Lathren","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Program on Integrative Medicine University of North Carolina School of Medicine Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyoung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Psychology and Neuroscience Duke University Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanee","family":"Lynch","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Program on Integrative Medicine University of North Carolina School of Medicine Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Curry","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Duke University Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"April","family":"Harris\u2010Britt","sequence":"additional","affiliation":[{"name":"AHB Center for Behavioral Health and Wellness Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Gaylord","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Program on Integrative Medicine University of North Carolina School of Medicine Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10880-019-09622-6"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-021-01825-3"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/01612840.2014.963902"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/nur.21870"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2014.12.036"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v067.i01"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.2.e119"},{"key":"e_1_2_9_10_1","volume-title":"The self\u2010compassion workbook for teens: Mindfulness and compassion skills to overcome self\u2010criticism and embrace who you are","author":"Bluth K.","year":"2017"},{"key":"e_1_2_9_11_1","volume-title":"The self\u2010compassionate teen: Mindfulness and compassion skills to conquer your critical inner voice","author":"Bluth K.","year":"2020"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10826-013-9830-2"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adolescence.2017.04.001"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12671-015-0476-6"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12671-014-0376-1"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/07435584211062126"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-7916(72)90045-6"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2018.05.022"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v045.i03"},{"issue":"3","key":"e_1_2_9_20_1","first-page":"159","article-title":"Mindfulness\u2010based intervention for female adolescents with chronic pain: A pilot randomized trial","volume":"25","author":"Chadi N.","year":"2016","journal-title":"Journal of the Canadian Academy of Child and Adolescent Psychiatry"},{"key":"e_1_2_9_21_1","unstructured":"Clarke G. 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